DRSC/TRiP Functional Genomics Resources

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Protein Alignment lbe and NKX6-1

DIOPT Version :10

Sequence 1:NP_524435.2 Gene:lbe / 42542 FlyBaseID:FBgn0011278 Length:479 Species:Drosophila melanogaster
Sequence 2:NP_006159.2 Gene:NKX6-1 / 4825 HGNCID:7839 Length:367 Species:Homo sapiens


Alignment Length:81 Identity:20/81 - (24%)
Similarity:32/81 - (39%) Gaps:20/81 - (24%)


- Green bases have known domain annotations that are detailed below.


  Fly   474 PNGCGKSSLFRILGELWPTWGGKVTKPPA--------GKLFYIPQRPYMTLGSLRDQI---IYPH 527
            |:|..:.|...:.||...|     .:||:        .||..:.:.......|||.:.   .:|.
Human     4 PSGAREDSGDGLTGEATGT-----EQPPSPASTSSLESKLQKLKRSLSFKTKSLRSKSADNFFPR 63

  Fly   528 THQEMKRRGKTDADLL 543
            |:.::    |..||||
Human    64 TNSDV----KPQADLL 75

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
lbeNP_524435.2 Homeodomain 354..410 CDD:459649
NKX6-1NP_006159.2 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 36..133 12/44 (27%)
Repressor domain. /evidence=ECO:0000250 102..268
Homeodomain 235..293 CDD:459649
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 294..367
Involved in DNA-binding. /evidence=ECO:0000250 306..367
Blue background indicates that the domain is not in the aligned region.

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