Protein Alignment lbe and NKX3-1

DIOPT Version :10

• Sequence 1: NP_524435.2
• Gene: lbe / 42542
• FlyBaseID: FBgn0011278
• Length: 479
• Species: Drosophila melanogaster
• Sequence 2: NP_006158.2
• Gene: NKX3-1 / 4824
• HGNCID: 7838
• Length: 234
• Species: Homo sapiens
• Alignment Length: 200
• Identity: 51/200 - (25%)
• Similarity: 74/200 - (37%)
• Gaps: 60/200 - (30%)

  Fly   389 AGFTARMTELTVVLKDLNSGRYERTMVNNSAIADAGDIGPGRGL-------LKFQDNLIKFEHVP 446
            ||....:||..|   .|..||..:| |.:.|.||..::....||       |: :..|.:|...|
Human     6 AGLCPGLTEEIV---QLLRGRKIKT-VADLAAADLEEVAQKCGLSYKALVALR-RVLLAQFSAFP 65

  Fly   447 LVTPNGDVLVKDLTFEVKSGMNVLVCGPNGCGKSSLFRIL------GELWPTWGGKVTKPPAGK- 504
            |   ||    .||..|:|:...:|     ..|..||.::|      |||....||    |.:||
Human    66 L---NG----ADLYEELKTSTAIL-----STGIGSLDKLLDAGLYTGELTEIVGG----PGSGKT 114

  Fly   505 -----------------LFYIPQRPYMTLGSLRDQIIYPHTHQEMKRRGKTDA-------DLLKY 545
                             :.|:.....||...|. |::...|..|.|:......       |:.:.
Human   115 QVCLCVAANVAHSLQQNVLYVDSNGGMTASRLL-QLLQARTQDEEKQASALQRIQVVHSFDIFQM 178

  Fly   546 LDLVQ 550
            ||::|
Human   179 LDMLQ 183

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
lbe	NP_524435.2	Homeodomain	354..410	CDD:459649	7/20 (35%)
NKX3-1	NP_006158.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..131		39/145 (27%)
		Homeodomain	125..181	CDD:459649	10/56 (18%)