Protein Alignment lbe and MSX2

DIOPT Version :10

• Sequence 1: NP_524435.2
• Gene: lbe / 42542
• FlyBaseID: FBgn0011278
• Length: 479
• Species: Drosophila melanogaster
• Sequence 2: NP_002440.2
• Gene: MSX2 / 4488
• HGNCID: 7392
• Length: 267
• Species: Homo sapiens
• Alignment Length: 253
• Identity: 70/253 - (27%)
• Similarity: 108/253 - (42%)
• Gaps: 49/253 - (19%)

  Fly   254 PAIIA--------SEDGSSERSQRSSSSNGSTECC-----SPRQAEKLEKLTTQEGSEEAQKKKS 305
            ||::|        :|..:.||..:.||...|.|..     .|::|   ..|..:..|..|..:..
Human    18 PAVVAGPGPGPGGAEGAAEERRVKVSSLPFSVEALMSDKKPPKEA---SPLPAESASAGATLRPL 79

  Fly   306 EEQPTGSGKSNGDTPLDALFQMTTKDFDESQDKSHLDIFSNRPQP---------------KKKRK 355
            .....|:.:::...||...|:..:...:.|:|.:.......|..|               |..||
Human    80 LLSGHGAREAHSPGPLVKPFETASVKSENSEDGAAWMQEPGRYSPPPRHMSPTTCTLRKHKTNRK 144

  Fly   356 SRTAFTNHQIFELEKRFLYQKYLSPADRDEIAASLGLSNAQVITWFQNRRAKQKR----DIEELK 416
            .||.||..|:..||::|..::|||.|:|.|.::||.|:..||..||||||||.||    ::|:||
Human   145 PRTPFTTSQLLALERKFRQKQYLSIAERAEFSSSLNLTETQVKIWFQNRRAKAKRLQEAELEKLK 209

  Fly   417 KDFDSVKVFSAHKSFLENVNDLSILKKKPMHESDMVGLAAAAAAAGMVVPVPGSVPMG 474
                     .|.|..|.:...|......|:..:.:.|  |:......|:|:|   |:|
Human   210 ---------MAAKPMLPSSFSLPFPISSPLQAASIYG--ASYPFHRPVLPIP---PVG 253

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
lbe	NP_524435.2	Homeodomain	354..410	CDD:459649	29/55 (53%)
MSX2	NP_002440.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..71		13/55 (24%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	116..147		5/30 (17%)
		Homeodomain	143..199	CDD:459649	29/55 (53%)