Protein Alignment lbe and MEOX1

DIOPT Version :10

• Sequence 1: NP_524435.2
• Gene: lbe / 42542
• FlyBaseID: FBgn0011278
• Length: 479
• Species: Drosophila melanogaster
• Sequence 2: NP_004518.1
• Gene: MEOX1 / 4222
• HGNCID: 7013
• Length: 254
• Species: Homo sapiens
• Alignment Length: 280
• Identity: 74/280 - (26%)
• Similarity: 99/280 - (35%)
• Gaps: 81/280 - (28%)

  Fly   150 SVSPP-PNANLLAPPASRPIAPSGGLLQPRTEPLDVHPAAAAAMLLPSGQIVRPWDHLLGPTMPV 213
            |:.|| |....|..|.|.....||....|.| |...|.              :| |.|...|...
Human    11 SLQPPAPVWGCLRNPHSEGNGASGLPHYPPT-PFSFHQ--------------KP-DFLATATAAY 59

  Fly   214 RPFIPSAL------LHYEQRLALDYHRQLQE----HFNAQAQLLRHMGMNPAIIASEDGSSERSQ 268
            ..|..|.|      |..|:.:..:.|....:    ||.. :...|.....||..:.|.|:|....
Human    60 PDFSASCLAATPHSLPQEEHIFTEQHPAFPQSPNWHFPV-SDARRRPNSGPAGGSKEMGTSSLGL 123

  Fly   269 RSSSSN--------GSTECCSPRQAEKLEKLTTQEGSEEAQKKKSEEQPTGSGKSNGDTPLDALF 325
            ..::..        |||       |.:.||.:::...|.:..:::..:|.||.|:
Human   124 VDTTGGPGDDYGVLGST-------ANETEKKSSRRRKESSDNQENRGKPEGSSKA---------- 171

  Fly   326 QMTTKDFDESQDKSHLDIFSNRPQPKKKRKSRTAFTNHQIFELEKRFLYQKYLSPADRDEIAASL 390
                                        ||.|||||..|:.|||..|.:..||:...|.|||.:|
Human   172 ----------------------------RKERTAFTKEQLRELEAEFAHHNYLTRLRRYEIAVNL 208

  Fly   391 GLSNAQVITWFQNRRAKQKR 410
            .||..||..||||||.|.||
Human   209 DLSERQVKVWFQNRRMKWKR 228

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
lbe	NP_524435.2	Homeodomain	354..410	CDD:459649	30/55 (55%)
MEOX1	NP_004518.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	86..178		23/137 (17%)
		Homeodomain	172..228	CDD:459649	30/55 (55%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	227..254		2/2 (100%)