Protein Alignment lbe and lab

DIOPT Version :10

• Sequence 1: NP_524435.2
• Gene: lbe / 42542
• FlyBaseID: FBgn0011278
• Length: 479
• Species: Drosophila melanogaster
• Sequence 2: NP_476613.1
• Gene: lab / 40817
• FlyBaseID: FBgn0002522
• Length: 629
• Species: Drosophila melanogaster
• Alignment Length: 649
• Identity: 140/649 - (21%)
• Similarity: 215/649 - (33%)
• Gaps: 243/649 - (37%)

  Fly    30 HHTHPHSHPH------------------PLQH-PRASTIDLLQQQQLLMQHHAAAAAAAAAAASG 75
            ||.|||::.:                  |.|| |...    |||||   ||............:|
  Fly    13 HHHHPHANAYDGYSTTTASAANASSYFAPQQHQPHLQ----LQQQQ---QHQHLQQPQQHLTYNG 70

  Fly    76 LTRSAVGNLPEDYFHPLKRLRMS---SSSSE-----------------PRDHTPSPPSAVPEPQT 120
            ...|:.||     ::|.::.:::   :||.:                 |..|..||.:|.....|
  Fly    71 YESSSPGN-----YYPQQQAQLTPPPTSSHQVVQQHQQQQQAQQQQLYPHSHLFSPSAAEYGITT 130

  Fly   121 NQTTKSAIEGV----KSFSIADILGHSEKQRE-------ESVSPPPNAN-LLAPPASRP------ 167
            :.||.:  .|.    .|.|.||....|:....       .:|:||.|:: :.|..||..
  Fly   131 STTTGN--PGTPLHPSSHSPADSYYESDSVHSYYATAAVATVAPPSNSSPITAANASATSNTQQQ 193

  Fly   168 ------IAPSGGLLQPRTEPLD-VHPAAAAAMLLP--SGQIVRPWDHLL----GPTMPVRPFIP- 218
                  |:...|::...   || ::|.|.|...:.  :|||...:..:|    .|.|.:....|
  Fly   194 QQQAAIISSENGMMYTN---LDCMYPTAQAQAPVHGYAGQIEEKYAAVLHASYAPGMVLEDQDPM 255

  Fly   219 ------SALLHYEQRLALDY------------------------------HR---QLQEHFNAQA 244
                  |.:.|::|.||..|                              |:   |:|:......
  Fly   256 MQQATQSQMWHHQQHLAGSYALDAMDSLGMHAHMHHGLPHGHLGNLANNPHQQQPQVQQQQQQPH 320

  Fly   245 QLLRH-MGMNPAI-------IASEDGSSERSQR-------------SSSSNG----STECCSPRQ 284
            |..:| ...:||.       ..|.:|...|.||             :|:|||    ||:..||..
  Fly   321 QQPQHPQNQSPAAHQQHHQNSVSPNGGMNRQQRGGVISPGSSTSSSTSASNGAHPASTQSKSPNH 385

  Fly   285 AEKLEKLTTQEGSEEAQKKKSEEQPT------------------------GSGKSNGDTPL---- 321
            :..:......:......|.::.:.|.                        |||..||...:
  Fly   386 SSSIPTYKWMQLKRNVPKPQAPKLPASGIASMHDYQMNGQLDMCRGGGGGGSGVGNGPVGVGGNG 450

  Fly   322 -----------DALFQMTTK-------------DFDESQDKSHLDIFSNRPQPKKKRKSRTAFTN 362
                       ::|....:.             ........|...:.||     .....||.|||
  Fly   451 SPGIGGVLSVQNSLIMANSAAAAGSAHPNGMGVGLGSGSGLSSCSLSSN-----TNNSGRTNFTN 510

  Fly   363 HQIFELEKRFLYQKYLSPADRDEIAASLGLSNAQVITWFQNRRAKQKRDIEE--LKKDFDSVKVF 425
            .|:.||||.|.:.:||:.|.|.|||.:|.|:..||..||||||.|||:.::|  :..|     :.
  Fly   511 KQLTELEKEFHFNRYLTRARRIEIANTLQLNETQVKIWFQNRRMKQKKRVKEGLIPAD-----IL 570

  Fly   426 SAHKSFLENVNDLSILKKKPMHE--------------SDMVGLAAAAAA-----AGMVVPVPGS 470
            :.|.:        |::.:||..:              ||:.|...|..|     ..|.:..|.|
  Fly   571 TQHST--------SVISEKPPQQQQPQPPELQLKSQGSDLGGNELATGAPSTPTTAMTLTAPTS 626

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
lbe	NP_524435.2	Homeodomain	354..410	CDD:459649	30/55 (55%)
lab	NP_476613.1	Homeodomain	505..558	CDD:459649	30/52 (58%)