Protein Alignment lbe and BSX

DIOPT Version :10

• Sequence 1: NP_524435.2
• Gene: lbe / 42542
• FlyBaseID: FBgn0011278
• Length: 479
• Species: Drosophila melanogaster
• Sequence 2: NP_001091639.1
• Gene: BSX / 390259
• HGNCID: 20450
• Length: 233
• Species: Homo sapiens
• Alignment Length: 318
• Identity: 82/318 - (25%)
• Similarity: 108/318 - (33%)
• Gaps: 138/318 - (43%)

  Fly   179 TEPLDVHPAAAAAMLLPSGQIVRPWDHLLGPTMPVRPFIPSALLHYEQRLA-----LDYHRQLQE 238
            |.||  |||::..   |:...:.  |.||....|:|...|.   |:...||     |||...|..
Human     6 TSPL--HPASSQR---PTSFFIE--DILLHKPKPLREVAPD---HFASSLASRVPLLDYGYPLMP 60

  Fly   239 HFNAQAQLLRHMGMNPAIIASEDGSSERSQRSSSSNGSTECCSPRQAEKLEK--------LTTQE 295
                          .|.::|                       |.....|.|        |||
Human    61 --------------TPTLLA-----------------------PHAHHPLHKGDHHHPYFLTT-- 86

  Fly   296 GSEEAQKKKSEEQPTGSGKSNGDTPLDALFQMTTKDFDESQDKSHLDIFSNRPQPK--------- 351
                            ||     .|:.|||                      |.|:
Human    87 ----------------SG-----MPVPALF----------------------PHPQHAELPGKHC 108

  Fly   352 KKRKSRTAFTNHQIFELEKRFLYQKYLSPADRDEIAASLGLSNAQVITWFQNRRAKQKRDIEELK 416
            ::||:||.|::.|:..|||||..|:|||..:|.|:|.:|.||..||.|||||||.|.|:   :|:
Human   109 RRRKARTVFSDSQLSGLEKRFEIQRYLSTPERVELATALSLSETQVKTWFQNRRMKHKK---QLR 170

  Fly   417 KDFDSVKVFSAHKSFLENVNDLSILKKKPMHESDMVGLAAAAAAAGMVVPVPGSVPMG 474
            |..|..|.....:|                .|....|..||.||...:     |:|.|
Human   171 KSQDEPKAPDGPES----------------PEGSPRGSEAATAAEARL-----SLPAG 207

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
lbe	NP_524435.2	Homeodomain	354..410	CDD:459649	31/55 (56%)
BSX	NP_001091639.1	Homeodomain	111..167	CDD:459649	31/55 (56%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	160..233		19/72 (26%)