Protein Alignment lbe and en

DIOPT Version :10

• Sequence 1: NP_524435.2
• Gene: lbe / 42542
• FlyBaseID: FBgn0011278
• Length: 479
• Species: Drosophila melanogaster
• Sequence 2: NP_523700.2
• Gene: en / 36240
• FlyBaseID: FBgn0000577
• Length: 552
• Species: Drosophila melanogaster
• Alignment Length: 538
• Identity: 123/538 - (22%)
• Similarity: 183/538 - (34%)
• Gaps: 171/538 - (31%)

  Fly    14 ESEISVGGAPSPLPTQ-HHTHPHSHPHPLQHPRASTIDLLQQQQLLMQ--------HH------- 62
            |...|...||||:..| .|.|........|..:...:..|||.|.|.|        ||
  Fly     4 EDRCSPQSAPSPITLQMQHLHHQQQQQQQQQQQMQHLHQLQQLQQLHQQQLAAGVFHHPAMAFDA 68

  Fly    63 AAAAAAAAAAASGLTRSAVGNLPEDYFHPLKRLRMSSSSSEPRDHTP--SPPSAVPEPQTNQTTK 125
            |||||||||||:....:|.           .:.|:|.|.|.....||  |.|..:.|.:::
  Fly    69 AAAAAAAAAAAAAHAHAAA-----------LQQRLSGSGSPASCSTPASSTPLTIKEEESD---- 118

  Fly   126 SAIEGVKSFSIADILGHSEKQREE------SVSPPPNANLLAPPASRPIAPSGGLLQPRTEPLDV 184
             ::.|..||.......:.|::.||      .|........|.|||.:.        |...:|
  Fly   119 -SVIGDMSFHNQTHTTNEEEEAEEDDDIDVDVDDTSAGGRLPPPAHQQ--------QSTAKP--- 171

  Fly   185 HPAAAAAMLLPS--GQIVRPWDHLLGPTMPVRPF--------IPSALLHYEQRLALDYHRQLQ-- 237
            ..|.:.:.:|..  |.:.:|...:.......|||        .|||....:   .|::.||.|
  Fly   172 SLAFSISNILSDRFGDVQKPGKSMENQASIFRPFEASRSQTATPSAFTRVD---LLEFSRQQQAA 233

  Fly   238 ----------------EHFNAQA----------QLLRHMGMNPAI-------------------- 256
                            ..||..|          ..||....|..|
  Fly   234 AAAATAAMMLERANFLNCFNPAAYPRIHEEIVQSRLRRSAANAVIPPPMSSKMSDANPEKSALGS 298

  Fly   257 ---------------------------IASEDGSSERSQRSS------SSNGSTECCSPRQAEKL 288
                                       :||...:|..|..||      ||:.|:..||...:...
  Fly   299 LCKAVSQIGQPAAPTMTQPPLSSSASSLASPPPASNASTISSTSSVATSSSSSSSGCSSAASSLN 363

  Fly   289 EKLTTQEGSEEAQKKKSEEQP----------TGSGKSNGDTPLDALFQMTTKDFDESQDKS--HL 341
            ...:::.|:..:....|..||          ..||..:.|.........||:........:  :.
  Fly   364 SSPSSRLGASGSGVNASSPQPQPIPPPSAVSRDSGMESSDDTRSETGSTTTEGGKNEMWPAWVYC 428

  Fly   342 DIFSNRP----------QPKKK----RKSRTAFTNHQIFELEKRFLYQKYLSPADRDEIAASLGL 392
            ..:|:||          |||.|    ::.||||::.|:..|::.|...:||:...|.::::.|||
  Fly   429 TRYSDRPSSGPRYRRPKQPKDKTNDEKRPRTAFSSEQLARLKREFNENRYLTERRRQQLSSELGL 493

  Fly   393 SNAQVITWFQNRRAKQKR 410
            :.||:..||||:|||.|:
  Fly   494 NEAQIKIWFQNKRAKIKK 511

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
lbe	NP_524435.2	Homeodomain	354..410	CDD:459649	22/55 (40%)
en	NP_523700.2	Homeodomain	455..511	CDD:459649	22/55 (40%)
		Engrail_1_C_sig	512..542	CDD:431338	123/538 (23%)