Protein Alignment lbe and Hmx1

DIOPT Version :10

• Sequence 1: NP_524435.2
• Gene: lbe / 42542
• FlyBaseID: FBgn0011278
• Length: 479
• Species: Drosophila melanogaster
• Sequence 2: NP_001101833.2
• Gene: Hmx1 / 360960
• RGDID: 1304928
• Length: 333
• Species: Rattus norvegicus
• Alignment Length: 344
• Identity: 91/344 - (26%)
• Similarity: 127/344 - (36%)
• Gaps: 89/344 - (25%)

  Fly   158 NLLAPPA--SRPIAPSGGLLQPRTE----PLDVHPAAAAAMLL-----------PSGQIVRPWDH 205
            ||||..|  |...|...|:.:...|    |.|..|..|....|           |.|: .|....
  Rat    23 NLLAAEAKGSGRAAQGDGVREEEEEDDDDPEDEDPEQARRRRLQRRRQQRAGSGPGGE-ARARAL 86

  Fly   206 LLGPTMPVRPFIPSALLHYEQRLALDYHRQLQEHFNAQAQLLRHMGMNPAIIASEDGSSERSQRS 270
            .|||..|..|..|.||   ....|..::.:.|..:..        |::|      |.|...|..:
  Rat    87 GLGPRPPPGPGPPFAL---GCGGATRWYPRAQGGYGG--------GLSP------DTSDRDSPET 134

  Fly   271 SSSNGSTECCSPR---QAEKLEKLTTQ---EGSEEAQKKKSEEQPTGSGKSNGDTPLDALFQMTT 329
            ....|..|...||   ......::|||   .|.|||  .:..|.|..:..:.|:.
  Rat   135 GEDMGRAESAWPRCPGPGAVPREVTTQGPAAGGEEA--AELAEAPAVAAAAAGEA---------- 187

  Fly   330 KDFDESQDKSHLDIFSNRPQPKKKRKSRTAFTNHQIFELEKRFLYQKYLSPADRDEIAASLGLSN 394
                               :..:::|:||.|:..|:|:||..|..::|||.|:|..:||||.|:.
  Rat   188 -------------------RGGRRKKTRTVFSRSQVFQLESTFDLKRYLSSAERAGLAASLQLTE 233

  Fly   395 AQVITWFQNRRAKQKRDIEELKKDFDSVKVFSAHKSFLENVNDLSILKKKPMHESDMVGLAAAAA 459
            .||..||||||.|.||   :|..:.::..:.......|..|..|       .|||       ..|
  Rat   234 TQVKIWFQNRRNKWKR---QLAAELEAASLSPPGAQRLVRVPVL-------YHES-------PPA 281

  Fly   460 AAGMVVPVPGSVPMGGAPP 478
            |.|..:|.|.:.|....||
  Rat   282 ATGPTLPFPLAPPAPAPPP 300

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
lbe	NP_524435.2	Homeodomain	354..410	CDD:459649	28/55 (51%)
Hmx1	NP_001101833.2	Homeodomain	193..249	CDD:459649	28/55 (51%)