DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment lbe and hlx1

DIOPT Version :9

Sequence 1:	NP_524435.2	Gene:	lbe / 42542	FlyBaseID:	FBgn0011278	Length:	479	Species:	Drosophila melanogaster
Sequence 2:	XP_009293289.1	Gene:	hlx1 / 327096	ZFINID:	ZDB-GENE-030131-5304	Length:	357	Species:	Danio rerio

Alignment Length:	385	Identity:	89/385 - (23%)
Similarity:	144/385 - (37%)	Gaps:	113/385 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly   127 AIEGVK--SFSIADIL--GHSEK-QREESVSPPPNANLLAPPASRPIAPSGGLLQPRTEPLDVHP 186
            |::.:|  ||.|||||  |.:|. |...|:.....|......:..|:.||     |.|....:||
Zfish    26 AVDSMKKPSFCIADILHVGDAENIQGSSSLMAHIGARAQVHSSGSPLRPS-----PVTPDARLHP 85

  Fly   187 AAAAAMLLPSGQIVRPWDHLLGPTMPVRPFIPSALLHY--EQRLALDYH---------RQLQEHF 240
            |           .:|...||........|...|..|.:  ::.|:.|:.         |.|....
Zfish    86 A-----------YLRHGIHLTSRAAINAPPPTSKDLKFGIDRILSTDFEPKSKESPSLRDLTSIV 139

  Fly   241 NAQAQLLRHMGMNPAIIASEDGSSERSQRSSSSNGSTECCSPRQAEKLEKLTTQEGSEEAQKKKS 305
            :...|...|:..:|...:.:...||    :||..||.                  |:...|..:.
Zfish   140 SPNRQSAVHVSASPYFASIDPTMSE----TSSLMGSI------------------GNAARQSGQH 182

  Fly   306 EEQPTGSGKSNGDTPLDALFQMTTKDFDESQDKSHLDIFSNRPQPKKKRK--SRTAFTNHQIFEL 368
            :.|.|..|:.         :.:.:||              ..||..|:::  ||..|:|.|...|
Zfish   183 QFQDTFPGRP---------YAVLSKD--------------TMPQTYKRKRSWSRAVFSNLQRKGL 224

  Fly   369 EKRFLYQKYLSPADRDEIAASLGLSNAQVITWFQNRRAKQKR--------------------DIE 413
            ||||..|||::..||.::||.|||::|||..||||||.|.:.                    :.|
Zfish   225 EKRFEIQKYVTKPDRKQLAAMLGLTDAQVKVWFQNRRMKWRHSKEAQAQKDKEKEQPDKSAAETE 289

  Fly   414 ELKKDFDSVKVFSAHKSFLENVNDLSILKKKPMHESDMVGLAAAAAAAGMVVPVPGSVPM 473
            :.::|....:...:...|.:...|.|.:....::::.::              :||.:|:
Zfish   290 QKERDDSECETEPSESEFEDGPEDKSDVDISDLNKASVI--------------IPGPLPV 335

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
lbe	NP_524435.2	Homeobox	356..410	CDD:395001	30/53 (57%)
hlx1	XP_009293289.1	Homeobox	212..265	CDD:278475	30/52 (58%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0488
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.810