Protein Alignment lbe and HOXC11

DIOPT Version :10

• Sequence 1: NP_524435.2
• Gene: lbe / 42542
• FlyBaseID: FBgn0011278
• Length: 479
• Species: Drosophila melanogaster
• Sequence 2: NP_055027.1
• Gene: HOXC11 / 3227
• HGNCID: 5123
• Length: 304
• Species: Homo sapiens
• Alignment Length: 281
• Identity: 62/281 - (22%)
• Similarity: 100/281 - (35%)
• Gaps: 81/281 - (28%)

  Fly   195 PSGQIVRPWDHLLGPTMPVRPFI-PSALLHYEQRLALDY-------HRQLQEHFNAQAQLLRHMG 251
            ||.||..|:...:.|...|...: ||...|:....:..|       ||:..........|:::.|
Human    55 PSRQISYPYSAQVPPVREVSYGLEPSGKWHHRNSYSSCYAAADELMHRECLPPSTVTEILMKNEG 119

  Fly   252 ------------MNPA-IIASEDGSSERSQRSSSSNGSTEC----------CSPRQAEKLEK--- 290
                        ..|| ..:|.:.:|...|.......:..|          ||.:...|.|.
Human   120 SYGGHHHPSAPHATPAGFYSSVNKNSVLPQAFDRFFDNAYCGGGDPPAEPPCSGKGEAKGEPEAP 184

  Fly   291 -----LTTQEGSEEAQKKKSEEQPTGSGKSN--------GDTPLDALFQMTTKDFDESQDKSHLD 342
                 .:..|...||:.::....|:.||.::        |..|
Human   185 PASGLASRAEAGAEAEAEEENTNPSSSGSAHSVAKEPAKGAAP---------------------- 227

  Fly   343 IFSNRPQPKKKRKSRTAFTNHQIFELEKRFLYQKYLSPADRDEIAASLGLSNAQVITWFQNRRAK 407
               |.|:.:||   |..::..||.|||:.|.:..|::...|.:::..|.|::.||..||||||.|
Human   228 ---NAPRTRKK---RCPYSKFQIRELEREFFFNVYINKEKRLQLSRMLNLTDRQVKIWFQNRRMK 286

  Fly   408 QKRDIEELKKDFDSVKVFSAH 428
            :|      |...|.::.||.:
Human   287 EK------KLSRDRLQYFSGN 301

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
lbe	NP_524435.2	Homeodomain	354..410	CDD:459649	20/55 (36%)
HOXC11	NP_055027.1	DUF3528	42..161	CDD:432284	20/105 (19%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	166..237		16/98 (16%)
		Homeodomain	233..289	CDD:459649	23/64 (36%)