Protein Alignment lbe and HOXC8

DIOPT Version :10

• Sequence 1: NP_524435.2
• Gene: lbe / 42542
• FlyBaseID: FBgn0011278
• Length: 479
• Species: Drosophila melanogaster
• Sequence 2: NP_073149.1
• Gene: HOXC8 / 3224
• HGNCID: 5129
• Length: 242
• Species: Homo sapiens
• Alignment Length: 193
• Identity: 52/193 - (26%)
• Similarity: 81/193 - (41%)
• Gaps: 48/193 - (24%)

  Fly   250 MGMNPAIIASEDGSSERSQRSS--------------SSNG------STECCSPRQAEKL---EKL 291
            :|.:.|::....||:...|.:|              |::|      |..|..  .|.|.   |.|
Human    32 VGRSHALVYGPGGSAPGFQHASHHVQDFFHHGTSGISNSGYQQNPCSLSCHG--DASKFYGYEAL 94

  Fly   292 TTQEGSEEAQKKKSEEQPTGSGKSNGDTPLDALFQMTTKDFDESQDKSHLDIFSN--------RP 348
            ..|......|:....:.|  ..||:.:|             :.|:.:.||:..|:        ||
Human    95 PRQSLYGAQQEASVVQYP--DCKSSANT-------------NSSEGQGHLNQNSSPSLMFPWMRP 144

  Fly   349 QPKKKRKSRTAFTNHQIFELEKRFLYQKYLSPADRDEIAASLGLSNAQVITWFQNRRAKQKRD 411
            ....:|..|..::.:|..||||.||:..||:...|.|::.:|||:..||..||||||.|.|::
Human   145 HAPGRRSGRQTYSRYQTLELEKEFLFNPYLTRKRRIEVSHALGLTERQVKIWFQNRRMKWKKE 207

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
lbe	NP_524435.2	Homeodomain	354..410	CDD:459649	25/55 (45%)
HOXC8	NP_073149.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	114..154		10/52 (19%)
		Antp-type hexapeptide	138..143		0/4 (0%)
		Homeodomain	150..206	CDD:459649	25/55 (45%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	206..242		0/2 (0%)