Protein Alignment lbe and HOXB9

DIOPT Version :10

• Sequence 1: NP_524435.2
• Gene: lbe / 42542
• FlyBaseID: FBgn0011278
• Length: 479
• Species: Drosophila melanogaster
• Sequence 2: NP_076922.1
• Gene: HOXB9 / 3219
• HGNCID: 5120
• Length: 250
• Species: Homo sapiens
• Alignment Length: 310
• Identity: 81/310 - (26%)
• Similarity: 108/310 - (34%)
• Gaps: 79/310 - (25%)

  Fly   127 AIEG-VKSFSIADILGHSEKQREESVSPPPNANLLAPPASRPIAPSGGLLQPRTEPLDVHPAAAA 190
            :|.| :.|:.:..|:.|..:.              ||||.   .|||.....|      .|..|.
Human     2 SISGTLSSYYVDSIISHESED--------------APPAK---FPSGQYASSR------QPGHAE 43

  Fly   191 AMLLPSGQIVRPWDHLLGPTMPV-----RPFIPSALLHYEQRLALDYHRQLQEHFNAQAQLLRHM 250
            .:..||..        ..|..||     .|..|    |....|...||..:|.           .
Human    44 HLEFPSCS--------FQPKAPVFGASWAPLSP----HASGSLPSVYHPYIQP-----------Q 85

  Fly   251 GMNPAIIASEDGSSERSQRSSSSNGSTECCSPRQAEKLEKLTTQEGSEEAQKKKSEEQPTGSGK- 314
            |:.||     :....|:....:..|.......:.|.|.|.|....|....|........|.:|:
Human    86 GVPPA-----ESRYLRTWLEPAPRGEAAPGQGQAAVKAEPLLGAPGELLKQGTPEYSLETSAGRE 145

  Fly   315 ---SN-----GDTPLDALFQMTTKDFDESQDKSHLD---IFSNRPQPKKKRKSRTAFTNHQIFEL 368
               ||     ||          .|..:.|:||...|   ..:|....:..||.|..:|.:|..||
Human   146 AVLSNQRPGYGD----------NKICEGSEDKERPDQTNPSANWLHARSSRKKRCPYTKYQTLEL 200

  Fly   369 EKRFLYQKYLSPADRDEIAASLGLSNAQVITWFQNRRAKQKRDIEELKKD 418
            ||.||:..||:...|.|:|..|.||..||..||||||.|.|:..:|..|:
Human   201 EKEFLFNMYLTRDRRHEVARLLNLSERQVKIWFQNRRMKMKKMNKEQGKE 250

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
lbe	NP_524435.2	Homeodomain	354..410	CDD:459649	28/55 (51%)
HOXB9	NP_076922.1	Hox9_act	1..172	CDD:461369	48/230 (21%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	21..47		10/48 (21%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	149..182		10/42 (24%)
		Homeodomain	186..242	CDD:459649	28/55 (51%)