Protein Alignment lbe and HOXB8

DIOPT Version :10

• Sequence 1: NP_524435.2
• Gene: lbe / 42542
• FlyBaseID: FBgn0011278
• Length: 479
• Species: Drosophila melanogaster
• Sequence 2: NP_076921.1
• Gene: HOXB8 / 3218
• HGNCID: 5119
• Length: 243
• Species: Homo sapiens
• Alignment Length: 249
• Identity: 63/249 - (25%)
• Similarity: 94/249 - (37%)
• Gaps: 70/249 - (28%)

  Fly   196 SGQIVRP--WDHLLGPTMPVRPFI---PSALLHYEQRLALDYHRQLQEHFNAQAQL-LRHMGMNP 254
            :|:.:||  :|......:..||.:   ||:...::      :..|:||.::..:.| ......||
Human    15 TGESLRPNYYDCGFAQDLGGRPTVVYGPSSGGSFQ------HPSQIQEFYHGPSSLSTAPYQQNP 73

  Fly   255 AIIASEDGSSERSQRSSSSNGSTECCSPRQAEKLE-------------KLTTQEG-SEEAQKKKS 305
            ..:|..           ...|:.....|.|.:.|.             ||....| .|||:..:.
Human    74 CAVACH-----------GDPGNFYGYDPLQRQSLFGAQDPDLVQYADCKLAAASGLGEEAEGSEQ 127

  Fly   306 EEQPTGSGKSNGDTPLDALFQMTTKDFDESQDKSHLDIFSNRPQPKK-KRKSRTAFTNHQIFELE 369
            ...||            .||...                  |||... :|:.|..::.:|..|||
Human   128 SPSPT------------QLFPWM------------------RPQAAAGRRRGRQTYSRYQTLELE 162

  Fly   370 KRFLYQKYLSPADRDEIAASLGLSNAQVITWFQNRRAKQKRDIEELKKDFDSVK 423
            |.||:..||:...|.|::.:|||:..||..||||||.|.|:  |..|..|.|.|
Human   163 KEFLFNPYLTRKRRIEVSHALGLTERQVKIWFQNRRMKWKK--ENNKDKFPSSK 214

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
lbe	NP_524435.2	Homeodomain	354..410	CDD:459649	25/55 (45%)
HOXB8	NP_076921.1	Antp-type hexapeptide	134..139		2/22 (9%)
		Homeodomain	147..203	CDD:459649	25/55 (45%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	203..243		5/14 (36%)