Protein Alignment lbe and HOXA9

DIOPT Version :10

• Sequence 1: NP_524435.2
• Gene: lbe / 42542
• FlyBaseID: FBgn0011278
• Length: 479
• Species: Drosophila melanogaster
• Sequence 2: NP_689952.1
• Gene: HOXA9 / 3205
• HGNCID: 5109
• Length: 272
• Species: Homo sapiens
• Alignment Length: 298
• Identity: 78/298 - (26%)
• Similarity: 102/298 - (34%)
• Gaps: 96/298 - (32%)

  Fly   153 PPPNANLLA-----PPAS------------RPIAPSGGLLQPRT-------EPLDVHPAAAAAML 193
            ||..|..||     .|.|            .|:..:|....|..       .|. |||.|..|..
Human    38 PPRQAATLAEHPDFSPCSFQSKATVFGASWNPVHAAGANAVPAAVYHHHHHHPY-VHPQAPVAAA 101

  Fly   194 LPSGQIVRPWDHLLGPTMPVRPF--IPSALLHYEQRLALDYHRQLQEHFNAQAQLLRHMGMNPAI 256
            .|.|:.:|.|   |.||.....|  :||:                           |..|:.|..
Human   102 APDGRYMRSW---LEPTPGALSFAGLPSS---------------------------RPYGIKPEP 136

  Fly   257 IASEDGSSERSQRSSSSNGSTECCSPR-QAEKLEKLTTQEGSEEAQKKKSEEQPTGSGKSNGDTP 320
            :::..|........:.|.....|.||. ..||       :.||.|..:.:.|..:|     ||.|
Human   137 LSARRGDCPTLDTHTLSLTDYACGSPPVDREK-------QPSEGAFSENNAENESG-----GDKP 189

  Fly   321 LDALFQMTTKDFDESQDKSHLDIFSNRP-----QPKKKRKSRTAFTNHQIFELEKRFLYQKYLSP 380
                                 .|..|.|     ..:..||.|..:|.||..||||.||:..||:.
Human   190 ---------------------PIDPNNPAANWLHARSTRKKRCPYTKHQTLELEKEFLFNMYLTR 233

  Fly   381 ADRDEIAASLGLSNAQVITWFQNRRAKQKRDIEELKKD 418
            ..|.|:|..|.|:..||..||||||.|.|:..::..||
Human   234 DRRYEVARLLNLTERQVKIWFQNRRMKMKKINKDRAKD 271

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
lbe	NP_524435.2	Homeodomain	354..410	CDD:459649	28/55 (51%)
HOXA9	NP_689952.1	Hox9_act	1..193	CDD:461369	45/218 (21%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	155..198		16/75 (21%)
		Homeodomain	207..263	CDD:459649	28/55 (51%)