Protein Alignment lbe and HOXA6

DIOPT Version :10

• Sequence 1: NP_524435.2
• Gene: lbe / 42542
• FlyBaseID: FBgn0011278
• Length: 479
• Species: Drosophila melanogaster
• Sequence 2: NP_076919.1
• Gene: HOXA6 / 3203
• HGNCID: 5107
• Length: 233
• Species: Homo sapiens
• Alignment Length: 239
• Identity: 62/239 - (25%)
• Similarity: 95/239 - (39%)
• Gaps: 61/239 - (25%)

  Fly   205 HLLGPTMPVRPFIPSALLHYEQRLALDYHRQLQEHFNAQAQLLR--HMGMNPAIIASEDGSSERS 267
            :.:.||.|  ..:||.                |:.|..|..|.:  :..:.|  ..:..|:|...
Human     4 YFVNPTFP--GSLPSG----------------QDSFLGQLPLYQAGYDALRP--FPASYGASSLP 48

  Fly   268 QRSSSSNGSTECCSPRQAEKLEKLTTQEGSEE-------AQKKKSEEQPTGSGKSNGDTPLDALF 325
            .::.:|.     |..:|:..:  |.....|.|       :.|..|...|:||||..|  |.|.|.
Human    49 DKTYTSP-----CFYQQSNSV--LACNRASYEYGASCFYSDKDLSGASPSGSGKQRG--PGDYLH 104

  Fly   326 ----QMTTKDFDESQDKSHLDIFSNR-------PQPKKK------------RKSRTAFTNHQIFE 367
                |....|....|.|:..|..::|       |..::.            |:.|..:|.:|..|
Human   105 FSPEQQYKPDSSSGQGKALHDEGADRKYTSPVYPWMQRMNSCAGAVYGSHGRRGRQTYTRYQTLE 169

  Fly   368 LEKRFLYQKYLSPADRDEIAASLGLSNAQVITWFQNRRAKQKRD 411
            |||.|.:.:||:...|.|||.:|.|:..|:..||||||.|.|::
Human   170 LEKEFHFNRYLTRRRRIEIANALCLTERQIKIWFQNRRMKWKKE 213

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
lbe	NP_524435.2	Homeodomain	354..410	CDD:459649	25/55 (45%)
HOXA6	NP_076919.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	89..127		14/39 (36%)
		Antp-type hexapeptide	136..141		1/4 (25%)
		Homeodomain	156..212	CDD:459649	25/55 (45%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	214..233		62/239 (26%)