Protein Alignment lbe and HOXA5

DIOPT Version :10

• Sequence 1: NP_524435.2
• Gene: lbe / 42542
• FlyBaseID: FBgn0011278
• Length: 479
• Species: Drosophila melanogaster
• Sequence 2: NP_061975.2
• Gene: HOXA5 / 3202
• HGNCID: 5106
• Length: 270
• Species: Homo sapiens
• Alignment Length: 291
• Identity: 78/291 - (26%)
• Similarity: 108/291 - (37%)
• Gaps: 87/291 - (29%)

  Fly   141 GHSEKQREESVSPPPNANLLAPPASRPIAPSGGLLQPRTEPLDVHPAAAAAMLLPSGQIVRPWDH 205
            |..|:.|..:.|..     .||...|...|:.....|:.:||   |.:|.|   ||
Human    65 GSGERARSYAASAS-----AAPAEPRYSQPATSTHSPQPDPL---PCSAVA---PS--------- 109

  Fly   206 LLGPTMPVRPFIPSALLHYEQRLALDYHRQLQEHFNAQAQLLRHMGMNPAIIASEDGSSERSQRS 270
                        |.:          |.|               |.|.|         |...|..:
Human   110 ------------PGS----------DSH---------------HGGKN---------SLSNSSGA 128

  Fly   271 SSSNGSTECCSPRQAEKLEKLTTQEGSEEAQKKKSEEQPTGSGKSNGDTPLDALFQMTTKDFDES 335
            |:..|||...|      .|.:.|..|:||.....||:....|..|........::..
Human   129 SADAGSTHISS------REGVGTASGAEEDAPASSEQASAQSEPSPAPPAQPQIYPW-------- 179

  Fly   336 QDKSHLDIFSNRPQPKKKRKSRTAFTNHQIFELEKRFLYQKYLSPADRDEIAASLGLSNAQVITW 400
            ..|.|:. ..|...|:.|| :|||:|.:|..||||.|.:.:||:...|.|||.:|.||..|:..|
Human   180 MRKLHIS-HDNIGGPEGKR-ARTAYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLSERQIKIW 242

  Fly   401 FQNRRAKQKRDIEELKKDFDSVKVFSAHKSF 431
            |||||.|.|:| .:||    |:.:.:|..:|
Human   243 FQNRRMKWKKD-NKLK----SMSMAAAGGAF 268

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
lbe	NP_524435.2	Homeodomain	354..410	CDD:459649	28/55 (51%)
HOXA5	NP_061975.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	75..175		35/171 (20%)
		Antp-type hexapeptide	176..181		0/12 (0%)
		Homeodomain	196..252	CDD:459649	29/56 (52%)