Protein Alignment lbe and hoxd3a

DIOPT Version :10

• Sequence 1: NP_524435.2
• Gene: lbe / 42542
• FlyBaseID: FBgn0011278
• Length: 479
• Species: Drosophila melanogaster
• Sequence 2: NP_571200.1
• Gene: hoxd3a / 30349
• ZFINID: ZDB-GENE-990415-120
• Length: 396
• Species: Danio rerio
• Alignment Length: 245
• Identity: 72/245 - (29%)
• Similarity: 103/245 - (42%)
• Gaps: 46/245 - (18%)

  Fly   261 DGSSERSQRSSSSNGSTECCSPRQAEKLEKLTTQEGSEEAQKKKSEEQPTGSGKSNGDTPL--DA 323
            :||..|...|..::........:||..|...:....:...|||||   |:.:|.|.. ||:  ..
Zfish    65 NGSCMRPSASQGNSQPESISEQQQAAPLAASSPSPSTNSTQKKKS---PSSNGSSTA-TPVISKQ 125

  Fly   324 LFQMTTKDFDESQDKSHLDIFSN------------RPQPKKKRKSRTAFTNHQIFELEKRFLYQK 376
            :|....:....::.||     :|            .|.|..|| .|||:|:.|:.||||.|.:.:
Zfish   126 IFPWMKETRQNAKQKS-----TNCPAAGETCDDKSPPGPASKR-VRTAYTSAQLVELEKEFHFNR 184

  Fly   377 YLSPADRDEIAASLGLSNAQVITWFQNRRAKQKRDIEELKKDFDSVKVFSAHKS----------- 430
            ||....|.|:|..|.|:..|:..||||||.|.|:| ::.|....|....|..:|
Zfish   185 YLCRPRRVEMANLLNLTERQIKIWFQNRRMKYKKD-QKSKGIMHSPLGHSPDRSPPLSGSNHIGY 248

  Fly   431 --FLENVNDLSILKKKP----MHESDMVGLAAAAAAAGMVVP----VPGS 470
              .|.|||.||.....|    ..:.::.||||..|..|..:|    .||:
Zfish   249 SGQLPNVNSLSYDAPSPPSFAKPQQNIYGLAAYTAPLGGCIPQQKRYPGT 298

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
lbe	NP_524435.2	Homeodomain	354..410	CDD:459649	26/55 (47%)
hoxd3a	NP_571200.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	18..163		23/106 (22%)
		COG5576	116..237	CDD:227863	41/128 (32%)
		Antp-type hexapeptide	126..131		1/4 (25%)
		Homeodomain	162..218	CDD:459649	27/56 (48%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	219..246		5/27 (19%)
		DUF4074	333..394	CDD:463833
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	364..396