Protein Alignment lbe and en2a

DIOPT Version :10

• Sequence 1: NP_524435.2
• Gene: lbe / 42542
• FlyBaseID: FBgn0011278
• Length: 479
• Species: Drosophila melanogaster
• Sequence 2: NP_571119.2
• Gene: en2a / 30243
• ZFINID: ZDB-GENE-980526-167
• Length: 265
• Species: Danio rerio
• Alignment Length: 236
• Identity: 59/236 - (25%)
• Similarity: 96/236 - (40%)
• Gaps: 64/236 - (27%)

  Fly   213 VRPF--------IPSALLHY--EQRLALDYHRQLQEHFNAQAQLLRHMGMNPAIIASEDGSSERS 267
            :||.        :|..:.::  :..|..|:.|:      .:|.:.|:          ||....|.
Zfish    24 IRPLLQAPGNLQLPHRITNFFIDNILRPDFGRK------KEANITRY----------EDNHGARE 72

  Fly   268 QRSSSSNGSTECCSPRQAEKLEKLTTQEGSEEAQKKKSEE-QPTGSGKSNGDTPLDALFQMTTKD 331
            ..:.:...:.:..|...||:.....|..|.:||:.:..|. :|.|   .|.|       |....:
Zfish    73 NHNPTGPSTGQVGSTVPAEEASTTHTSSGGKEAEIESEEPLKPRG---ENVD-------QCLGSE 127

  Fly   332 FDESQDKS--------------HLDIFSNRP-------QPKKK------RKSRTAFTNHQIFELE 369
            .|.||..|              :...:|:||       :||||      ::.|||||..|:..|:
Zfish   128 SDSSQSNSNGQTGQGMLWPAWVYCTRYSDRPSSGPRSRKPKKKAASKEDKRPRTAFTAEQLQRLK 192

  Fly   370 KRFLYQKYLSPADRDEIAASLGLSNAQVITWFQNRRAKQKR 410
            ..|...:||:...|..:|..|||:.:|:..||||:|||.|:
Zfish   193 AEFQTNRYLTEQRRQSLAQELGLNESQIKIWFQNKRAKIKK 233

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
lbe	NP_524435.2	Homeodomain	354..410	CDD:459649	23/55 (42%)
en2a	NP_571119.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..30		2/5 (40%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	65..142		20/86 (23%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	155..180		7/24 (29%)
		Homeodomain	177..233	CDD:459649	23/55 (42%)
		Engrail_1_C_sig	234..264	CDD:431338	59/236 (25%)