Protein Alignment lbe and Nkx1-1

DIOPT Version :9

• Sequence 1: NP_524435.2
• Gene: lbe / 42542
• FlyBaseID: FBgn0011278
• Length: 479
• Species: Drosophila melanogaster
• Sequence 2: XP_234082.6
• Gene: Nkx1-1 / 298981
• RGDID: 1564874
• Length: 443
• Species: Rattus norvegicus
• Alignment Length: 510
• Identity: 119/510 - (23%)
• Similarity: 166/510 - (32%)
• Gaps: 174/510 - (34%)

  Fly     6 TMRPASPAESEISVGGAPSPLPTQHHTHPHSHPHPLQHPRASTIDLLQQQQLLMQHHAAAAAAAA 70
            |..||:|.:    :...|.|.|.   ..|.|.|.|                      .|.||.|.
  Rat     3 TSGPAAPGD----IPALPPPPPP---PEPGSGPAP----------------------PAPAATAR 38

  Fly    71 AAASGLTRSAVGNLPEDYFHPLKRLRMSSS-SSEPRDHTPSPPSAVPEPQTNQTTKSAIEGVKSF 134
            .|..|  |:.:...|.....|   |.:|.: .:.|.....:.|:|.|.|             .||
  Rat    39 DAMDG--RAELPIFPRAGVPP---LAVSDTVPAVPDGAGAARPAAPPRP-------------TSF 85

  Fly   135 SIADILG----HSEKQREESVSP--PPNANLLAPPASRPIAPSGGLLQPRTEPLDVHPAAAAAML 193
            |:.|||.    :|.::|...:.|  |......||.|..|:..:.| ..||.| |:....:||..:
  Rat    86 SVLDILDPNKFNSRRRRCVLLGPVVPATCAPCAPAACVPVPAASG-RSPRAE-LERRALSAATGV 148

  Fly   194 LPSGQIVRPWDHLLGPTMPVRPFIPSALLHYEQRLALDYHRQLQEHFNAQAQLLRHMGMNPAIIA 258
                                     :|....|.....|.:|..:...|..:.   ..|.:|. ..
  Rat   149 -------------------------AAATGAEPTSTGDSYRADEAEANGYSS---GSGRSPT-AD 184

  Fly   259 SED--------------------------GSSERSQRSSSSNGSTECCSPRQAEKLEKLTTQEGS 297
            |||                          ||.....|.|..:|:.|         :|.....|.:
  Rat   185 SEDEAPEEDEDEDQAPEVQDVQGTEEPRGGSGGLGARGSGCSGAAE---------VEASPVDEAA 240

  Fly   298 EEAQKKKSEEQP----TGSGKSN-GDTPLDALFQMTTKDFDESQDKSHLDIFSNRPQPKKKRKSR 357
            ....:..|...|    |.:|..| |.||..|  .:.||   ..:.::..|..|.:|     |::|
  Rat   241 APGPRGNSPGAPGPPVTAAGAGNAGSTPQGA--AVATK---PKRKRTGSDSKSGKP-----RRAR 295

  Fly   358 TAFTNHQIFELEKRFLYQKYLSPADRDEIAASLGLSNAQVITWFQNRRAKQKRDIEELKKDFDSV 422
            ||||..|:..||.:|...:|||..:|..:|.||.|:..||..||||||.|.|
  Rat   296 TAFTYEQLVALENKFKATRYLSVCERLNLALSLSLTETQVKIWFQNRRTKWK------------- 347

  Fly   423 KVFSAHKSFLENVNDLSILKKKPMHESDMVGLAAAAAAAGMVVPVPGSVPMGGAP 477
                               |:.|       |...:|...|...|.||:.|..|.|
  Rat   348 -------------------KQNP-------GADTSAPTGGGGGPGPGAGPGAGLP 376

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
lbe	NP_524435.2	Homeobox	356..410	CDD:395001	26/53 (49%)
Nkx1-1	XP_234082.6	Homeobox	295..347	CDD:278475	26/51 (51%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0488
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810