Protein Alignment lbe and Hmx3

DIOPT Version :10

• Sequence 1: NP_524435.2
• Gene: lbe / 42542
• FlyBaseID: FBgn0011278
• Length: 479
• Species: Drosophila melanogaster
• Sequence 2: NP_001099772.1
• Gene: Hmx3 / 293537
• RGDID: 1559927
• Length: 356
• Species: Rattus norvegicus
• Alignment Length: 408
• Identity: 103/408 - (25%)
• Similarity: 156/408 - (38%)
• Gaps: 115/408 - (28%)

  Fly    98 SSSSSEPRDHTPSPPSAVPEPQTNQTTKSAIEGVKSFSIADILGHSEKQREESVSPPPN-----A 157
            |.::|.|   .|.||...|.|:.:           .|||.::|.....:......|||.     |
  Rat     9 SGTASAP---PPQPPPQPPAPKES-----------PFSIRNLLNGDHHRPPPKPQPPPRTLFAPA 59

  Fly   158 NLLAPPASRPIAPSGGLLQPRTEPLDVHPAAAAAMLLPSGQIVRPWDHLLGPTMPVRPFIPSALL 222
            :..|..|:...|.:.|.|:          .||...|...|.:..|           |..||:
  Rat    60 SAAAAAAAAAAAAAKGALE----------GAAGFALSQVGDLAFP-----------RFEIPA--- 100

  Fly   223 HYEQRLALDYHRQLQEHFNAQAQLLRHMGMNPA------------IIASEDGSSERSQRSSSSNG 275
               ||.||..|               ::..:||            .:...:.|.:...|.||...
  Rat   101 ---QRFALPAH---------------YLERSPAWWYPYTLTPAGGHLPRPEASEKALLRDSSPAS 147

  Fly   276 STECCSP------------RQAEKLEKLTTQEGSEEAQKKKSEEQPTGSGKSNGDTPLDALFQMT 328
            .|:..||            ..::..:::..:|...|..||:.|..|..:|.:.|.|....    .
  Rat   148 GTDRDSPDPLLKADPDHKELDSKSPDEIILEESDSEEGKKEGEAVPGAAGTTVGATAATP----G 208

  Fly   329 TKDFDESQDKSHLDIFSNRPQPK---KKRKSRTAFTNHQIFELEKRFLYQKYLSPADRDEIAASL 390
            ::|:....|.         |:.|   :|:|:||.|:..|:|:||..|..::|||.::|..:||||
  Rat   209 SEDWKAGADS---------PEKKPACRKKKTRTVFSRSQVFQLESTFDMKRYLSSSERAGLAASL 264

  Fly   391 GLSNAQVITWFQNRRAKQKRDIEELKKDFDSVKVFSAHKSFLENVNDLSILKKKPMHESDMVGLA 455
            .|:..||..||||||.|.||   :|..:.::..:..|....:..|..|       .||:.....|
  Rat   265 HLTETQVKIWFQNRRNKWKR---QLAAELEAANLSHAAAQRIVRVPIL-------YHENSAAEGA 319

  Fly   456 AAAAAAGMVVPVPGSVPM 473
            ||||.|    |||.|.|:
  Rat   320 AAAAGA----PVPVSQPL 333

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
lbe	NP_524435.2	Homeodomain	354..410	CDD:459649	27/55 (49%)
Hmx3	NP_001099772.1	Homeodomain	228..284	CDD:459649	27/55 (49%)