Protein Alignment lbe and Hoxd1

DIOPT Version :10

• Sequence 1: NP_524435.2
• Gene: lbe / 42542
• FlyBaseID: FBgn0011278
• Length: 479
• Species: Drosophila melanogaster
• Sequence 2: NP_001099354.1
• Gene: Hoxd1 / 288151
• RGDID: 1309179
• Length: 328
• Species: Rattus norvegicus
• Alignment Length: 380
• Identity: 86/380 - (22%)
• Similarity: 113/380 - (29%)
• Gaps: 154/380 - (40%)

  Fly   108 TPSPPSAV-----PEPQTNQTTKSAIEGVKSFSIADILGHSEKQREESVSPPPNANLLAPPASRP 167
            |||||.|.     |:|..::.....:||.                .|..:.|.:|.......|.|
  Rat    65 TPSPPVAPAQPPGPQPAASRYAPCTLEGA----------------YERGAAPASAAEYGFLGSGP 113

  Fly   168 IAPSGGLLQPRTEPLDVHPAAAAAMLLPSGQIVRPWDHLLGPTMPVRPFIPSALLHYEQRLALDY 232
            .....|.|....:....|...|.:.:..||                ..|:.|.
  Rat   114 AFDFPGALGRAADDSGPHVHYATSAVFSSG----------------GSFLLSG------------ 150

  Fly   233 HRQLQEHFNAQAQLLRHMGMNPAIIAS-EDGSSERSQRSSSSNGSTECCSPRQAEKLEKLTTQEG 296
                |..|.|.|:    .|..||.:.. .||.....|..|.:.|:   | |:.|.....|.....
  Rat   151 ----QVDFAAFAE----PGPFPACLKEPADGHPGPFQTVSPAPGA---C-PKPASPTSGLPAAHS 203

  Fly   297 SEEAQKKKSEEQPTGSGKSNGDTPLDALFQMTTKDFDESQDKSHLDIFSNRPQPKKKRKS----- 356
            :.|..|.|                                          |..|||.:.|
  Rat   204 TFEWMKVK------------------------------------------RNAPKKSKLSEYGAT 226

  Fly   357 ------RTAFTNHQIFELEKRFLYQKYLSPADRDEIAASLGLSNAQVITWFQNRRAKQKRDIEEL 415
                  ||.|:..|:.||||.|.:.|||:.|.|.|||..|.|::.||..||||||.|||:...|
  Rat   227 SPSSAIRTNFSTKQLTELEKEFHFNKYLTRARRMEIANCLQLNDTQVKIWFQNRRMKQKKRERE- 290

  Fly   416 KKDFDSVKVFSAHKSFLENVNDLSILKKKPMHESDMVGLAAAAAAAGMVVPVPGS 470
                                                 ||.|.||:... :.:|||
  Rat   291 -------------------------------------GLLATAASVAS-LQLPGS 307

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
lbe	NP_524435.2	Homeodomain	354..410	CDD:459649	30/66 (45%)
Hoxd1	NP_001099354.1	COG5576	<208..325	CDD:227863	46/181 (25%)
		Homeodomain	233..286	CDD:459649	29/52 (56%)