DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment lbe and VENTX

DIOPT Version :9

Sequence 1:	NP_524435.2	Gene:	lbe / 42542	FlyBaseID:	FBgn0011278	Length:	479	Species:	Drosophila melanogaster
Sequence 2:	NP_055283.1	Gene:	VENTX / 27287	HGNCID:	13639	Length:	258	Species:	Homo sapiens

Alignment Length:	166	Identity:	50/166 - (30%)
Similarity:	71/166 - (42%)	Gaps:	33/166 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly   263 SSERSQRSSSSNGSTE-----CCS-----PRQAE----KLEKLTTQEGSEEAQKKKSEEQPTGSG 313
            |..|..:..||.||.:     .||     ||.|:    .|.......|:.|..:..|.::..||
Human     6 SPPRGPQQLSSFGSVDWLSQSSCSGPTHTPRPADFSLGSLPGPGQTSGAREPPQAVSIKEAAGS- 69

  Fly   314 KSNGDTPLDALFQMTTKDFDESQDKSHLDIFSNRPQPKKKRKSRTAFTNHQIFELEKRFLYQKYL 378
             ||...|...:..:                 |..|...:..:.|||||..|:..||..|.:.:||
Human    70 -SNLPAPERTMAGL-----------------SKEPNTLRAPRVRTAFTMEQVRTLEGVFQHHQYL 116

  Fly   379 SPADRDEIAASLGLSNAQVITWFQNRRAKQKRDIEE 414
            ||.:|..:|..:.||..|:.|||||||.|.||.:::
Human   117 SPLERKRLAREMQLSEVQIKTWFQNRRMKHKRQMQD 152

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
lbe	NP_524435.2	Homeobox	356..410	CDD:395001	26/53 (49%)
VENTX	NP_055283.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..93		22/105 (21%)
		Homeobox	95..147	CDD:306543	26/51 (51%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	227..248
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0488
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810