DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment lbe and tlx1

DIOPT Version :9

Sequence 1:NP_524435.2 Gene:lbe / 42542 FlyBaseID:FBgn0011278 Length:479 Species:Drosophila melanogaster
Sequence 2:NP_739571.1 Gene:tlx1 / 266964 ZFINID:ZDB-GENE-021021-2 Length:301 Species:Danio rerio


Alignment Length:115 Identity:45/115 - (39%)
Similarity:67/115 - (58%) Gaps:5/115 - (4%)


- Green bases have known domain annotations that are detailed below.


  Fly   344 FSNRPQPKKKRKSRTAFTNHQIFELEKRFLYQKYLSPADRDEIAASLGLSNAQVITWFQNRRAKQ 408
            :.||..|||| |.||:||..||.||||||..||||:.|:|..:|.:|.:::|||.|||||||.|.
Zfish   168 YQNRTPPKKK-KPRTSFTRLQICELEKRFHRQKYLASAERAALAKALKMTDAQVKTWFQNRRTKW 231

  Fly   409 KR----DIEELKKDFDSVKVFSAHKSFLENVNDLSILKKKPMHESDMVGL 454
            :|    :.|..::..:.:.:....::|.:.:|.........:|.|.:..|
Zfish   232 RRQTAEEREAERQQANRILMQLQQEAFQKTINQPVTPDPICLHNSSLFAL 281

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
lbeNP_524435.2 Homeobox 356..410 CDD:395001 31/53 (58%)
tlx1NP_739571.1 Homeobox 179..232 CDD:278475 31/52 (60%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG0488
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 1 1.000 - -
TreeFam 00.000 Not matched by this tool.
ZFIN 00.000 Not matched by this tool.
32.810

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