Protein Alignment lbe and NKX2-8

DIOPT Version :10

• Sequence 1: NP_524435.2
• Gene: lbe / 42542
• FlyBaseID: FBgn0011278
• Length: 479
• Species: Drosophila melanogaster
• Sequence 2: NP_055175.2
• Gene: NKX2-8 / 26257
• HGNCID: 16364
• Length: 239
• Species: Homo sapiens
• Alignment Length: 222
• Identity: 56/222 - (25%)
• Similarity: 81/222 - (36%)
• Gaps: 81/222 - (36%)

  Fly   279 CCSPRQAEKLEKLTTQEGSEEAQKKKSEEQPTGSGKSNGDTPLDALFQMTTKDFDESQDKSHLDI 343
            |.:...:|:....::.|.|.|.....|.::|:....|.|.   ||
Human    40 CAAWLDSERGHYPSSDESSLETSPPDSSQRPSARPASPGS---DA-------------------- 81

  Fly   344 FSNRPQPKKKRKSRTAFTNHQIFELEKRFLYQKYLSPADRDEIAASLGLSNAQVITWFQNRRAKQ 408
                   :|::|.|..|:..|..|||:||..|:|||..:|:::|:.|.|:..||..||||.|.|.
Human    82 -------EKRKKRRVLFSKAQTLELERRFRQQRYLSAPEREQLASLLRLTPTQVKIWFQNHRYKL 139

  Fly   409 KRDIEELKKDFDSVKVFSAHKSFLENVNDLSILKKKPMHESDMVGLAAAAAAAGM----VVPV-- 467
            ||           .:...|.:|                  .|:...|...||.|:    ||||
Human   140 KR-----------ARAPGAAES------------------PDLAASAELHAAPGLLRRVVVPVLV 175

  Fly   468 --------PGSVPMG--------GAPP 478
                    .|...:|        ||||
Human   176 RDGQPCGGGGGGEVGTAAAQEKCGAPP 202

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
lbe	NP_524435.2	Homeodomain	354..410	CDD:459649	25/55 (45%)
NKX2-8	NP_055175.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..87		12/76 (16%)
		Homeodomain	85..141	CDD:459649	25/55 (45%)