Protein Alignment lbe and EVX1

DIOPT Version :10

• Sequence 1: NP_524435.2
• Gene: lbe / 42542
• FlyBaseID: FBgn0011278
• Length: 479
• Species: Drosophila melanogaster
• Sequence 2: NP_001980.1
• Gene: EVX1 / 2128
• HGNCID: 3506
• Length: 407
• Species: Homo sapiens
• Alignment Length: 365
• Identity: 83/365 - (22%)
• Similarity: 121/365 - (33%)
• Gaps: 127/365 - (34%)

  Fly   130 GVKSFSIADILGHSEKQREESVSP----PPNANLLAPPASRPIAPSGGLLQPRTEPLD------- 183
            |.:..::::.:|....:..|.:.|    .|.|   .|||:|.....|    |..||:|
Human    21 GKRVSNLSEAVGSPLPEPPEKMVPRGCLSPRA---VPPATRERGGGG----PEEEPVDGLAGSAA 78

  Fly   184 ---VHPAAAAAMLLPSGQIVRPWDHLLGPTMPVRPFIPSALLHYEQRLALDYHRQLQEHF----- 240
               ..|..|.|.:|..|......|.|.|...|......|           |::.:::...
Human    79 GPGAEPQVAGAAMLGPGPPAPSVDSLSGQGQPSSSDTES-----------DFYEEIEVSCTPDCA 132

  Fly   241 --NAQAQLLRHMGMNPAIIASEDGSSERSQRSSSSNGSTECCSPRQAEKLEKLTTQEGSEEAQKK 303
              ||:.|..:..| :.|::.|.:|.||    :..|||.
Human   133 TGNAEYQHSKGSG-SEALVGSPNGGSE----TPKSNGG--------------------------- 165

  Fly   304 KSEEQPTGSGKSNGDTPLDALFQMTTKDFDESQDKSHLDIFSNRPQPKKKRKSRTAFTNHQIFEL 368
                  :|.|.|.|.....|..||                          |:.|||||..||..|
Human   166 ------SGGGGSQGTLACSASDQM--------------------------RRYRTAFTREQIARL 198

  Fly   369 EKRFLYQKYLSPADRDEIAASLGLSNAQVITWFQNRRAKQKRDIEELKKDFDSVKVFSAHKSFLE 433
            ||.|..:.|:|...|.|:||:|.|....:..||||||.|.||....:.....:...|..:.
Human   199 EKEFYRENYVSRPRRCELAAALNLPETTIKVWFQNRRMKDKRQRLAMTWPHPADPAFYTYM---- 259

  Fly   434 NVNDLSILKKKPMHESDMVGLAAAAAAAGMVVPVPGSVPM 473
                                ::.||||.|:..|.|..:|:
Human   260 --------------------MSHAAAAGGLPYPFPSHLPL 279

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
lbe	NP_524435.2	Homeodomain	354..410	CDD:459649	27/55 (49%)
EVX1	NP_001980.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	29..120		25/108 (23%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	137..179		14/79 (18%)
		Homeodomain	184..240	CDD:459649	27/55 (49%)