Protein Alignment lbe and Hoxc10

DIOPT Version :10

• Sequence 1: NP_524435.2
• Gene: lbe / 42542
• FlyBaseID: FBgn0011278
• Length: 479
• Species: Drosophila melanogaster
• Sequence 2: NP_034592.2
• Gene: Hoxc10 / 209448
• MGIID: 96192
• Length: 342
• Species: Mus musculus
• Alignment Length: 453
• Identity: 99/453 - (21%)
• Similarity: 150/453 - (33%)
• Gaps: 146/453 - (32%)

  Fly     1 MLCPPTMRPASPAESEISVGGAPSPLPTQHHTHPHSHPHPLQHPRASTIDLLQQQQL---LMQHH 62
            |.||..:.|.|.||...:.||..                  ::.|.:.:.:......   :|:..
Mouse     1 MTCPRNVTPNSYAEPLAAPGGGE------------------RYNRNAGMYMQSGSDFNCGVMRGC 47

  Fly    63 AAAAAAAAAAASGLTRSAVGNLP------EDYFHPLKRLRMSSSSSEPRDHTPSPPSAVPEPQTN 121
            ..|.:.:.....|....|:...|      :.:..|....|:......|......|||
Mouse    48 GLAPSLSKRDEGGSPNLALNTYPSYLSQLDSWGDPKAAYRLEQPVGRPLSSCSYPPS-------- 104

  Fly   122 QTTKSAIEGVKSFSIADILGHSEKQREESVSPPPNANLLAPPASR--------PIAPSGGLLQPR 178
                     ||..::..:  :|.::|.:|   .|.|.|.:.|...        |: ||.....|.
Mouse   105 ---------VKEENVCCM--YSAEKRAKS---GPEAALYSHPLPESCLGEHEVPV-PSYYRASPS 154

  Fly   179 TEPLDVHPAAAAAMLLPSGQIVRPWDHLLGPTMPVRPFIPSALLHYEQRLALDYHRQLQEHFNAQ 243
            ...||..|..|.|     .:...|                     :|||.:|          |.:
Mouse   155 YSALDKTPHCAGA-----NEFEAP---------------------FEQRASL----------NPR 183

  Fly   244 AQLLRHMGMNPAIIASEDGSSERSQRSSSSNGSTE------CCSPRQAEKLEKLTTQEGS----- 297
            .:.|....:...:...|...|: ||..|.:...||      ..||.::|| |:..|.:.|
Mouse   184 TEHLESPQLGGKVSFPETPKSD-SQTPSPNEIKTEQSLAGPKASPSESEK-ERAKTADSSPDTSD 246

  Fly   298 EEAQKKKSEEQPTGSGKSNGDTPLDALFQMTTKDFDESQDKSHLDIFSNRPQPKKKRKSRTAFTN 362
            .||:::...|..||                                  |....|..||.|..:|.
Mouse   247 NEAKEEIKAENTTG----------------------------------NWLTAKSGRKKRCPYTK 277

  Fly   363 HQIFELEKRFLYQKYLSPADRDEIAASLGLSNAQVITWFQNRRAKQKR-----DIEELKKDFD 420
            ||..||||.||:..||:...|.||:.::.|::.||..||||||.|.|:     .|.||..:|:
Mouse   278 HQTLELEKEFLFNMYLTRERRLEISKTINLTDRQVKIWFQNRRMKLKKMNRENRIRELTSNFN 340

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
lbe	NP_524435.2	Homeodomain	354..410	CDD:459649	27/55 (49%)
Hoxc10	NP_034592.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..20		7/18 (39%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	186..271		23/120 (19%)
		Homeodomain	269..325	CDD:459649	27/55 (49%)