Protein Alignment lbe and Nkx1-2

DIOPT Version :9

• Sequence 1: NP_524435.2
• Gene: lbe / 42542
• FlyBaseID: FBgn0011278
• Length: 479
• Species: Drosophila melanogaster
• Sequence 2: NP_033149.1
• Gene: Nkx1-2 / 20231
• MGIID: 104806
• Length: 305
• Species: Mus musculus
• Alignment Length: 288
• Identity: 71/288 - (24%)
• Similarity: 110/288 - (38%)
• Gaps: 75/288 - (26%)

  Fly   206 LLGPTMPVRPFIPSALLHYEQRLALDYHRQLQEHFNAQAQLLRHMGMNPAIIASEDGSSERSQRS 270
            :|.|....|..:|...|     .||:..:.|:|                         .|..|.:
Mouse    25 ILDPQKFTRAALPPVRL-----AALEAKKSLEE-------------------------VEAGQDA 59

  Fly   271 SSSN--GSTECCSPRQAEK-LEKLTTQEGSEEAQKKKSEE-----QP-TGSGKSNGDTPLDALFQ 326
            .|.|  ||.|  :|....: ::..:..||||..:::::|:     || ...|...|.....|:..
Mouse    60 CSGNPIGSQE--TPDAVGRGIDPGSPVEGSEAEEEEEAEDAGRAHQPERWQGVHEGSPEARAVAV 122

  Fly   327 MTTKDFDESQDKSHLDIFSNRPQPK-------KKRKSRTAFTNHQIFELEKRFLYQKYLSPADRD 384
            .|.:...|....|.....|.||:.:       |.|::|||||..|:..||.:|...:|||..:|.
Mouse   123 GTEESGAEGLPASPGSPGSPRPRRRRAESSCAKPRRARTAFTYEQLVALENKFRATRYLSVCERL 187

  Fly   385 EIAASLGLSNAQVITWFQNRRAKQKRDIEELKKDFDSVKVFSAHKSFLENVNDLSILK-----KK 444
            .:|.||.|:..||..||||||.|.|:                      :|......::     .:
Mouse   188 NLALSLSLTETQVKIWFQNRRTKWKK----------------------QNPGADGAVQAGGGAPQ 230

  Fly   445 PMHESDMVGLAAAAAAAGMVVPVPGSVP 472
            |.....:.|...:|..:....||||::|
Mouse   231 PGTPGAVAGGGGSATGSSPGPPVPGALP 258

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
lbe	NP_524435.2	Homeobox	356..410	CDD:395001	26/53 (49%)
Nkx1-2	NP_033149.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	51..158		26/133 (20%)
		Homeobox	160..212	CDD:278475	26/51 (51%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	210..257		10/68 (15%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0488
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900