Protein Alignment lbe and EMX1

DIOPT Version :10

• Sequence 1: NP_524435.2
• Gene: lbe / 42542
• FlyBaseID: FBgn0011278
• Length: 479
• Species: Drosophila melanogaster
• Sequence 2: NP_004088.2
• Gene: EMX1 / 2016
• HGNCID: 3340
• Length: 290
• Species: Homo sapiens
• Alignment Length: 295
• Identity: 82/295 - (27%)
• Similarity: 110/295 - (37%)
• Gaps: 74/295 - (25%)

  Fly   169 APSGGLLQ----PRTEPLDVHPAAAAAMLLPSGQ--------IVR------------PWDHLLGP 209
            ||..|.|.    |||.|      |||.|..|:.:        :.:            ...|||..
Human    13 APGRGALPRARLPRTAP------AAATMFQPAAKRGFTIESLVAKDGGTGGGTGGGGAGSHLLAA 71

  Fly   210 TMPVRPFIPSALLHYEQRLALDYHRQLQEHFNAQAQLLRHMGMNPAIIASEDGSSERSQRSSSSN 274
            .....|..|:| |:|....|            |:|..:...   ||..|:..|        .|..
Human    72 AASEEPLRPTA-LNYPHPSA------------AEAAFVSGF---PAAAAAGAG--------RSLY 112

  Fly   275 GSTECCSPRQAEKLEKLTTQEGSEEAQKKKSEEQPTGS--GKSNGDTPL--------DALFQMTT 329
            |..|...| :|.....||.....   |...|..||..|  |..:.| ||        :..|....
Human   113 GGPELVFP-EAMNHPALTVHPAH---QLGASPLQPPHSFFGAQHRD-PLHFYPWVLRNRFFGHRF 172

  Fly   330 KDFDESQDKSHLDIFSNRPQPKKKRKSRTAFTNHQIFELEKRFLYQKYLSPADRDEIAASLGLSN 394
            :..|..||    .:..:.|..:|.::.||||:..|:..||:.|....|:..|:|.::|.||.||.
Human   173 QASDVPQD----GLLLHGPFARKPKRIRTAFSPSQLLRLERAFEKNHYVVGAERKQLAGSLSLSE 233

  Fly   395 AQVITWFQNRRAKQKRD-IEELKKDFDSVKVFSAH 428
            .||..||||||.|.||. :||...:.:..|..|.|
Human   234 TQVKVWFQNRRTKYKRQKLEEEGPESEQKKKGSHH 268

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
lbe	NP_524435.2	Homeodomain	354..410	CDD:459649	25/55 (45%)
EMX1	NP_004088.2	Homeodomain	193..249	CDD:459649	25/55 (45%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	249..290		6/20 (30%)