Protein Alignment lbe and Nkx2-3

DIOPT Version :10

• Sequence 1: NP_524435.2
• Gene: lbe / 42542
• FlyBaseID: FBgn0011278
• Length: 479
• Species: Drosophila melanogaster
• Sequence 2: NP_032725.1
• Gene: Nkx2-3 / 18089
• MGIID: 97348
• Length: 362
• Species: Mus musculus
• Alignment Length: 260
• Identity: 69/260 - (26%)
• Similarity: 106/260 - (40%)
• Gaps: 91/260 - (35%)

  Fly   192 MLLPSGQIVRPWDHLLGPTMPV--RPFIPSALLHYEQRLALDYHRQLQEHFNA---QAQLLRHMG 251
            |:|||               ||  .||....:|:.||          |.||:.   ||:|.:|..
Mouse     1 MMLPS---------------PVTSTPFSVKDILNLEQ----------QRHFHGAHLQAELEQHFH 40

  Fly   252 MNPAIIASEDGS--SERSQRSSSSNGS------------------------------TECCSPRQ 284
            ..|.::|:.:|:  |:..:......|.                              ..|..|::
Mouse    41 SAPCMLATAEGTQFSDAGEEDEEEEGEKLSYLNSLAAAEGHGDSGLCPQSYVHTVLRDACSGPKE 105

  Fly   285 AEKLEKLTTQEGSEEAQKKKSEEQPTGSGKSNGDTPLDALFQMTTKDFDESQDKSHLDIFSNRPQ 349
            .|  |::.::...:..|.|||.| ..|..|::.|                          ..||:
Mouse   106 QE--EEVVSERSQKSCQLKKSLE-AAGDCKTSED--------------------------GERPK 141

  Fly   350 PKKKRKSRTAFTNHQIFELEKRFLYQKYLSPADRDEIAASLGLSNAQVITWFQNRRAKQKRDIEE 414
            |:.:||.|..|:..|:||||:||..|:|||..:|:.:|:||.|::.||..||||||.|.||..::
Mouse   142 PRSRRKPRVLFSQAQVFELERRFKQQRYLSAPEREHLASSLKLTSTQVKIWFQNRRYKCKRQRQD 206

  Fly   415  414
            Mouse   207  206

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
lbe	NP_524435.2	Homeodomain	354..410	CDD:459649	29/55 (53%)
Nkx2-3	NP_032725.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	126..149		9/49 (18%)
		Homeodomain	146..202	CDD:459649	29/55 (53%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	203..222		0/4 (0%)