Protein Alignment lbe and Msx2

DIOPT Version :10

• Sequence 1: NP_524435.2
• Gene: lbe / 42542
• FlyBaseID: FBgn0011278
• Length: 479
• Species: Drosophila melanogaster
• Sequence 2: NP_038629.2
• Gene: Msx2 / 17702
• MGIID: 97169
• Length: 267
• Species: Mus musculus
• Alignment Length: 266
• Identity: 72/266 - (27%)
• Similarity: 107/266 - (40%)
• Gaps: 75/266 - (28%)

  Fly   254 PAIIASE---DGSSERSQRSSSSNGSTECCSPRQAEKLEKLTTQEGSEEA---QKKKSEEQPT-- 310
            ||::|..   .|.:|         ||.|       |:..|:::...|.||   .||..:|.|.
Mouse    18 PAVLAGPGPGPGGAE---------GSAE-------ERRVKVSSLPFSVEALMSDKKPPKESPAVP 66

  Fly   311 ------------------GSGKSNGDTPLDALFQMTTKDFDESQDKSHLDIFSNRPQP------- 350
                              |...::...||...|:..:...:.|:|.:.......|..|
Mouse    67 PDCASAGAVLRPLLLPGHGVRDAHSPGPLVKPFETASVKSENSEDGAPWIQEPGRYSPPPRHMSP 131

  Fly   351 --------KKKRKSRTAFTNHQIFELEKRFLYQKYLSPADRDEIAASLGLSNAQVITWFQNRRAK 407
                    |..||.||.||..|:..||::|..::|||.|:|.|.::||.|:..||..||||||||
Mouse   132 TTCTLRKHKTNRKPRTPFTTSQLLALERKFRQKQYLSIAERAEFSSSLNLTETQVKIWFQNRRAK 196

  Fly   408 QKR----DIEELKKDFDSVKVFSAHKSFLENVNDLSILKKKPMHESDMVGLAAAAAAAGMVVPVP 468
            .||    ::|:||         .|.|..|.:...|......|:..:.:.|  |:......|:|:|
Mouse   197 AKRLQEAELEKLK---------MAAKPMLPSGFSLPFPINSPLQAASIYG--ASYPFHRPVLPIP 250

  Fly   469 GSVPMG 474
               |:|
Mouse   251 ---PVG 253

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
lbe	NP_524435.2	Homeodomain	354..410	CDD:459649	29/55 (53%)
Msx2	NP_038629.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..42		9/39 (23%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	104..132		4/27 (15%)
		Homeodomain	143..199	CDD:459649	29/55 (53%)