Protein Alignment lbe and DLX6

DIOPT Version :10

• Sequence 1: NP_524435.2
• Gene: lbe / 42542
• FlyBaseID: FBgn0011278
• Length: 479
• Species: Drosophila melanogaster
• Sequence 2: NP_005213.3
• Gene: DLX6 / 1750
• HGNCID: 2919
• Length: 293
• Species: Homo sapiens
• Alignment Length: 364
• Identity: 81/364 - (22%)
• Similarity: 125/364 - (34%)
• Gaps: 163/364 - (44%)

  Fly   144 EKQREESVSPPPNANLLAPPASRPIAPSGGLLQPRTE-----------PLD-VHPAAAAAMLLPS 196
            ::|:::...|||      ||...|        ||.::           ||. :|.|||||
Human    36 QQQQQQQQQPPP------PPPPPP--------QPHSQQSSPAMAGAHYPLHCLHSAAAAA----- 81

  Fly   197 GQIVRPWDHLLGPTMPVRPFIPSALLHYEQRLALDYHRQLQEHFNAQAQLLRHMGMNPAIIASED 261
                                  :|..|:.      :|.|...|
Human    82 ----------------------AAGSHHH------HHHQHHHH---------------------- 96

  Fly   262 GSSERSQRSSSSNGSTECCSPRQAEKLEKLTTQEGSEEAQKKKSEEQPTGSGKSNGDTPLDALFQ 326
            ||...|...:|.|..:....|..:.          |:.:...:|....:.:.::.||
Human    97 GSPYASGGGNSYNHRSLAAYPYMSH----------SQHSPYLQSYHNSSAAAQTRGD-------- 143

  Fly   327 MTTKDFDESQDKSHLDIFSN-----RPQPKKKRKSRTAFTNHQIFELEKRFLYQKYLSPADRDEI 386
                  |..|.|:  .:..|     ..:.||.||.||.:::.|:..|..||...:||:..:|.|:
Human   144 ------DTDQQKT--TVIENGEIRFNGKGKKIRKPRTIYSSLQLQALNHRFQQTQYLALPERAEL 200

  Fly   387 AASLGLSNAQVITWFQNRRAKQKRDIEELKKDFDSVKVFSAHKSFLENVNDLSILKK--KPMHES 449
            ||||||:..||..||||:|:|.|:                             :||:  .| |||
Human   201 AASLGLTQTQVKIWFQNKRSKFKK-----------------------------LLKQGSNP-HES 235

  Fly   450 D-MVGLAA--------------AAAAAGMVVP----VPG 469
            | :.|.||              :|:|.|:.:|    :||
Human   236 DPLQGSAALSPRSPALPPVWDVSASAKGVSMPPNSYMPG 274

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
lbe	NP_524435.2	Homeodomain	354..410	CDD:459649	26/55 (47%)
DLX6	NP_005213.3	Homeodomain	168..224	CDD:459649	26/55 (47%)