Protein Alignment lbe and Hoxd3

DIOPT Version :10

• Sequence 1: NP_524435.2
• Gene: lbe / 42542
• FlyBaseID: FBgn0011278
• Length: 479
• Species: Drosophila melanogaster
• Sequence 2: NP_034598.2
• Gene: Hoxd3 / 15434
• MGIID: 96207
• Length: 433
• Species: Mus musculus
• Alignment Length: 310
• Identity: 76/310 - (24%)
• Similarity: 106/310 - (34%)
• Gaps: 89/310 - (28%)

  Fly   208 GPTMPVRPFIPSALLHYEQRLALDYHR---QLQEHFNAQAQLLRHMGMNPAIIASEDGSSERSQR 269
            |.:.|.:|:.|.|..:   .|..||..   .:|.  :|..:...|.|      |..:||..|...
Mouse    42 GYSTPHQPYPPPAAAN---SLDSDYPSSACSIQS--SAPLRAPAHKG------AELNGSCMRPGT 95

  Fly   270 SSSSNGSTECCSPRQAEKLEKLTTQEGSEEAQKKKSEEQP------------------TGSG--- 313
            .:|..|.                   |..:.....||:||                  .|||
Mouse    96 GNSQGGG-------------------GGNQPPGLNSEQQPPQPPPPPPPTLPPSSPTNPGSGVPA 141

  Fly   314 ---------KSNGDTPLDALFQMTTKDFDESQDKSHLDIFSNR------PQPKKKRKSRTAFTNH 363
                     .|:..|....:|....:....|:.|:........      |.|..|| .|||:|:.
Mouse   142 KKTKGGLSASSSSSTISKQIFPWMKESRQNSKQKNSCATSGENCEDKSPPGPASKR-VRTAYTSA 205

  Fly   364 QIFELEKRFLYQKYLSPADRDEIAASLGLSNAQVITWFQNRRAKQKRDIEELKKDFDSVKVFSAH 428
            |:.||||.|.:.:||....|.|:|..|.|:..|:..||||||.|.|:|              ...
Mouse   206 QLVELEKEFHFNRYLCRPRRVEMANLLNLTERQIKIWFQNRRMKYKKD--------------QKA 256

  Fly   429 KSFLENVNDLSILKKKPMHESDMVGLAAAAAAAGMVVPVPGSVPMGGAPP 478
            |..|.     |...:.|.....:.|.|...|.:|.:.||||......:||
Mouse   257 KGILH-----SPAGQSPERSPPLGGAAGHVAYSGQLPPVPGLAYDAPSPP 301

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
lbe	NP_524435.2	Homeodomain	354..410	CDD:459649	26/55 (47%)
Hoxd3	NP_034598.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	44..198		34/184 (18%)
		Antp-type hexapeptide	161..166		1/4 (25%)
		Homeodomain	196..252	CDD:459649	27/56 (48%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	258..280		5/26 (19%)
		DUF4074	370..431	CDD:463833
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	401..433