Protein Alignment lbe and Hoxd1

DIOPT Version :10

• Sequence 1: NP_524435.2
• Gene: lbe / 42542
• FlyBaseID: FBgn0011278
• Length: 479
• Species: Drosophila melanogaster
• Sequence 2: NP_034597.2
• Gene: Hoxd1 / 15429
• MGIID: 96201
• Length: 328
• Species: Mus musculus
• Alignment Length: 338
• Identity: 82/338 - (24%)
• Similarity: 101/338 - (29%)
• Gaps: 151/338 - (44%)

  Fly   108 TPSPP-----SAVPEPQTNQTTKSAIEGVKSFSIADILGHSEKQREESVSPPPNA--NLLA---- 161
            |||||     |.||:|...:.....:||.               .|...:|...|  ..|.
Mouse    65 TPSPPAGPAQSPVPQPAAPRYAPCTLEGA---------------YERGAAPASAAEYGFLGSGPA 114

  Fly   162 ---PPASRPIAPSGGLLQPRTEPLDVHPAAAAAM-----LLPSGQI-----VRPWDHLLGPTMPV 213
               |.|....|..||        ..||.|.:|..     .|.|||:     ..|     ||
Mouse   115 FDFPGALGRAADEGG--------AHVHYATSAVFSGGGSFLLSGQVDFAAFGEP-----GP---- 162

  Fly   214 RPFIPSALLHYEQRLALDYHRQLQEHFNAQAQLLRHMGMNPAIIASEDGSSERSQRSSSSNGSTE 278
               .|:.|                              ..||     ||.....|..|.:.|:
Mouse   163 ---FPACL------------------------------KEPA-----DGHPGPFQTVSPAPGA-- 187

  Fly   279 CCSPRQAEKLEKLTTQEGSEEAQKKKSEEQPTGSGKSNGDTPLDALFQMTTKDFDESQDKSHLDI 343
             | |:.|.....|.....:.|..|.|
Mouse   188 -C-PKPASPTSSLPAAHSTFEWMKVK--------------------------------------- 211

  Fly   344 FSNRPQPKKKRKS-----------RTAFTNHQIFELEKRFLYQKYLSPADRDEIAASLGLSNAQV 397
               |..|||.:.|           ||.|:..|:.||||.|.:.|||:.|.|.|||..|.|::.||
Mouse   212 ---RNAPKKSKLSEYGATSPPSAIRTNFSTKQLTELEKEFHFNKYLTRARRIEIANCLQLNDTQV 273

  Fly   398 ITWFQNRRAKQKR 410
            ..||||||.|||:
Mouse   274 KIWFQNRRMKQKK 286

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
lbe	NP_524435.2	Homeodomain	354..410	CDD:459649	30/66 (45%)
Hoxd1	NP_034597.2	PRK12323	<11..217	CDD:481241	49/267 (18%)
		Antp-type hexapeptide	204..209		1/4 (25%)
		Homeodomain	233..286	CDD:459649	29/52 (56%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	304..328