Protein Alignment lbe and Hoxb4

DIOPT Version :10

• Sequence 1: NP_524435.2
• Gene: lbe / 42542
• FlyBaseID: FBgn0011278
• Length: 479
• Species: Drosophila melanogaster
• Sequence 2: NP_034589.3
• Gene: Hoxb4 / 15412
• MGIID: 96185
• Length: 250
• Species: Mus musculus
• Alignment Length: 413
• Identity: 93/413 - (22%)
• Similarity: 121/413 - (29%)
• Gaps: 172/413 - (41%)

  Fly    71 AAASGLTRSAVGNLPEDYFHPLKRLRMSSSSSEPRDHTPSPPSAVPEPQTNQTTKSAIEGVKSFS 135
            |.:|.|..|   |..:..|.|.:  ..|.|...|.||:|...:.      .|..:|..:...:|
Mouse     2 AMSSFLINS---NYVDPKFPPCE--EYSQSDYLPSDHSPGYYAG------GQRRESGFQPEAAF- 54

  Fly   136 IADILGHSEK---QREESV---SPPPNANLLAPPASRPIAPSGGLLQPRTEPLDVHPAAAAAMLL 194
                 |....   ||..:.   .|||     .||...|..|.|  |.||.   .|.|.|.|  ||
Mouse    55 -----GRRAPCTVQRYAACRDPGPPP-----PPPPPPPPPPPG--LSPRA---PVQPTAGA--LL 102

  Fly   195 PSGQIVRPWDHLLGPTMPVRPFIPSALLHYEQRLALDYHRQLQEHFNAQAQLLRHMGMNPAIIAS 259
            |
Mouse   103 P---------------------------------------------------------------- 103

  Fly   260 EDGSSERSQRSSSSNGSTECCSPRQAEKLEKLTTQEGSEEAQKKKSEEQPTGSGKSNGDTPLDAL 324
            |.|  :||:..|||.....|.                          :.|.....|:.......:
Mouse   104 EPG--QRSEAVSSSPPPPPCA--------------------------QNPLHPSPSHSACKEPVV 140

  Fly   325 FQMTTKDFDESQDKSHLDIFSNRPQPKKKRKSRTAFTNHQIFELEKRFLYQKYLSPADRDEIAAS 389
            :..        ..|.|:...:......:.::||||:|..|:.||||.|.|.:||:...|.|||.:
Mouse   141 YPW--------MRKVHVSTVNPNYAGGEPKRSRTAYTRQQVLELEKEFHYNRYLTRRRRVEIAHA 197

  Fly   390 LGLSNAQVITWFQNRRAKQKRDIEELKKDFDSVKVFSAHKSFLENVNDLSILKKKPMHESDMVGL 454
            |.||..|:..||||||.|.|:|                ||  |.|..               :..
Mouse   198 LCLSERQIKIWFQNRRMKWKKD----------------HK--LPNTK---------------IRS 229

  Fly   455 AAAAAAAGMVVPVPGSVPMGGAP 477
            ...|.|||    .|...|.||.|
Mouse   230 GGTAGAAG----GPPGRPNGGPP 248

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
lbe	NP_524435.2	Homeodomain	354..410	CDD:459649	29/55 (53%)
Hoxb4	NP_034589.3	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..133		47/251 (19%)
		Antp-type hexapeptide	140..145		0/12 (0%)
		Homeodomain	162..218	CDD:459649	29/55 (53%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	219..250		14/67 (21%)