Protein Alignment lbe and Hoxa4

DIOPT Version :10

• Sequence 1: NP_524435.2
• Gene: lbe / 42542
• FlyBaseID: FBgn0011278
• Length: 479
• Species: Drosophila melanogaster
• Sequence 2: NP_032291.1
• Gene: Hoxa4 / 15401
• MGIID: 96176
• Length: 285
• Species: Mus musculus
• Alignment Length: 472
• Identity: 101/472 - (21%)
• Similarity: 135/472 - (28%)
• Gaps: 230/472 - (48%)

  Fly    12 PAESEISVGGAPSPLPTQHHTHPHSHPH-PLQHPRASTIDLLQQQQLLMQHHAAAAAAAAAAASG 75
            |...:.:|||.|.      :..|.|.|| |..:|                 |||
Mouse    29 PGGGDGAVGGGPG------YPRPQSAPHLPAPNP-----------------HAA----------- 59

  Fly    76 LTRSAVGNLPEDYFHPLKRLRMSSSSSEPRDHTPSPPSAVPEPQTNQTTKSAIEGVKSFSIADIL 140
                   ..|..|:.|..|     ..|.|....|:|.:|.|..                    ..
Mouse    60 -------RQPPAYYAPRAR-----EPSYPGGLYPAPAAACPYA--------------------CR 92

  Fly   141 GHSEKQREESVSPPPNANLLAPPASRPIAPSGGLLQPRTEPLDVHPAAAAAMLLPSGQIVRPWDH 205
            |.|..:.|:  ||.|.|:  ..||.:|.||      ||      |.|.
Mouse    93 GASPARPEQ--SPAPGAH--PSPAPQPPAP------PR------HCAP----------------- 124

  Fly   206 LLGPTMPVRPFIPSALLHYEQRLALDYHRQLQEHFNAQAQLLRHMGMNPAIIASEDGSSERSQRS 270
              |||.|                                                         :
Mouse   125 --GPTTP---------------------------------------------------------A 130

  Fly   271 SSSNGSTECCSPRQAEKLEKLTTQEGSEEAQKKKSEEQPTGSGKSNGDTPLDALFQMTTKDFDES 335
            .::.||...|....|::                       |.....|..|:  ::....|....:
Mouse   131 VATGGSAPACPLLLADQ-----------------------GPAGPKGKEPV--VYPWMKKIHVSA 170

  Fly   336 QDKSHLDIFSNRPQPKKKRKSRTAFTNHQIFELEKRFLYQKYLSPADRDEIAASLGLSNAQVITW 400
            .:.|:     |..:||   :||||:|..|:.||||.|.:.:||:...|.|||.:|.||..||..|
Mouse   171 VNSSY-----NGGEPK---RSRTAYTRQQVLELEKEFHFNRYLTRRRRIEIAHTLCLSERQVKIW 227

  Fly   401 FQNRRAKQKRDIEELKKDFDSVKVFSAHKSFLENVNDLSILKKKPMHESDMVGLAAAAAAAG--- 462
            |||||.|.|:|                ||           |....|..|:     .|:|.||
Mouse   228 FQNRRMKWKKD----------------HK-----------LPNTKMRSSN-----TASAPAGPPG 260

  Fly   463 ---MVVPVPGSVPMGGA 476
               ...|.|...|:.||
Mouse   261 KAQTHSPHPHPHPLPGA 277

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
lbe	NP_524435.2	Homeodomain	354..410	CDD:459649	29/55 (53%)
Hoxa4	NP_032291.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	19..70		17/81 (21%)
		PHA03247	<43..161	CDD:223021	46/294 (16%)
		Antp-type hexapeptide	159..164		0/4 (0%)
		Homeodomain	181..237	CDD:459649	30/58 (52%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	238..285		15/72 (21%)