Protein Alignment lbe and Gbx2

DIOPT Version :10

• Sequence 1: NP_524435.2
• Gene: lbe / 42542
• FlyBaseID: FBgn0011278
• Length: 479
• Species: Drosophila melanogaster
• Sequence 2: NP_034392.1
• Gene: Gbx2 / 14472
• MGIID: 95668
• Length: 348
• Species: Mus musculus
• Alignment Length: 395
• Identity: 100/395 - (25%)
• Similarity: 138/395 - (34%)
• Gaps: 124/395 - (31%)

  Fly   111 PPS--AVPEPQTNQTTKSAIEGVKSFSIADILGHSEKQREESVSPP-PNAN-------------- 158
            |||  .:..|..:.|         :|||..::|          ||| |:..
Mouse     6 PPSLMMMQRPLGSST---------AFSIDSLIG----------SPPQPSPGHFVYTGYPMFMPYR 51

  Fly   159 --LLAPPASRPIAPSGGLLQPRTEPLDVH------PAAAAAML-------------LPSGQIVRP 202
              :|.||...|.|.....|||...|...|      |....:.|             ||.|....|
Mouse    52 PVVLPPPPPPPPALPQAALQPALPPAHPHHQIPSLPTGFCSSLAQGMALTSTLMATLPGGFSASP 116

  Fly   203 WDHLLGPTMPVRPFIPSALL---HYEQRLALDYHRQLQEHFNAQAQLLRHMGMNPAIIASEDGSS 264
            ...   .....|.|.|..|.   ::::..||            ||.             :|||.:
Mouse   117 QHQ---EAAAARKFAPQPLPGGGNFDKAEAL------------QAD-------------AEDGKA 153

  Fly   265 ERSQRSSSSNGSTECCSPRQA--EKLEKLTTQEGSEEAQKKKSEEQPTGSGKS---NGDTPLDAL 324
                 ..:..||....|..:|  ..|......:|.:|:   |.|:.|.|..:|   ..|....:.
Mouse   154 -----FLAKEGSLLAFSAAEAVQASLVGAVRGQGKDES---KVEDDPKGKEESFSLESDVDYSSD 210

  Fly   325 FQMTTKDFDESQDKSHLDIFSNRPQ----------PKKKRKSRTAFTNHQIFELEKRFLYQKYLS 379
            ..:..:...:.:|..|  .....||          ..|.|:.|||||:.|:.||||.|..:||||
Mouse   211 DNLPGQTAHKEEDPGH--ALEETPQSGGAAGSTTSTGKNRRRRTAFTSEQLLELEKEFHCKKYLS 273

  Fly   380 PADRDEIAASLGLSNAQVITWFQNRRAKQKRDIEELKKDFDSVKVFSAHKSFLENVNDLSILKKK 444
            ..:|.:||.:|.||..||..||||||||.||           ||..:|:....|...:..|:...
Mouse   274 LTERSQIAHALKLSEVQVKIWFQNRRAKWKR-----------VKAGNANSKTGEPSRNPKIVVPI 327

  Fly   445 PMHES 449
            |:|.|
Mouse   328 PVHVS 332

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
lbe	NP_524435.2	Homeodomain	354..410	CDD:459649	32/55 (58%)
Gbx2	NP_034392.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	59..81		6/21 (29%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	111..139		6/30 (20%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	179..251		14/76 (18%)
		Homeodomain	248..304	CDD:459649	32/55 (58%)