Protein Alignment lbe and Cdx4

DIOPT Version :10

• Sequence 1: NP_524435.2
• Gene: lbe / 42542
• FlyBaseID: FBgn0011278
• Length: 479
• Species: Drosophila melanogaster
• Sequence 2: NP_031700.1
• Gene: Cdx4 / 12592
• MGIID: 88362
• Length: 282
• Species: Mus musculus
• Alignment Length: 425
• Identity: 86/425 - (20%)
• Similarity: 130/425 - (30%)
• Gaps: 207/425 - (48%)

  Fly     4 PPTMRPASPAESEI----SVGGAPSPLPTQHHTHPHSHPHPLQHPRASTIDLLQQQQLLMQHHAA 64
            |.|:|  ||..|..    :.||:.||||..:.|....:||.:.:|..|.:|          .|..
Mouse    15 PGTLR--SPGGSSTAGVGTSGGSGSPLPASNFTAAPVYPHYVGYPHMSNMD----------PHGP 67

  Fly    65 AAAAAAAAASGLTRSAVGNLPEDYFHPLKRLRMSSSSSEPRDH---TPSPPSAVPEPQTNQTTKS 126
            :..|                            .||..|.||:.   .|.|||.:.....|..|
Mouse    68 SLGA----------------------------WSSPYSPPREDWSTYPGPPSTMGTVPMNDMT-- 102

  Fly   127 AIEGVKSFSIADILGHSEKQREESVSPPPNANLLAPPASRPIAPSGGLLQPRTEPLDVHPAAAAA 191
                      :.:.|            .|:.:.|.|.:.   |.:||.|          |.||:
Mouse   103 ----------SPVFG------------SPDYSTLGPTSG---ASNGGSL----------PDAAS- 131

  Fly   192 MLLPSGQIVRPWDHLLGPTMPVRPFIPSALLHYEQRLALDYHRQLQEHFNAQAQLLRHMGMNPAI 256
                                             |..::||
Mouse   132 ---------------------------------ESLVSLD------------------------- 138

  Fly   257 IASEDGSSERSQRSSSSNGSTECCSPRQAEKLEKLTTQEGSEEAQKKKSEEQPTGSGKSNGDTPL 321
                          |.::|:|   ||.::..         |..|..:|: .|.||
Mouse   139 --------------SGTSGAT---SPSRSRH---------SPYAWMRKT-VQVTG---------- 166

  Fly   322 DALFQMTTKDFDESQDKSHLDIFSNRPQPKKKRKSRTAFTNHQIFELEKRFLYQKYLSPADRDEI 386
                                       :.:.|.|.|..:|:||..||||.|...:|::...:.|:
Mouse   167 ---------------------------KTRTKEKYRVVYTDHQRLELEKEFHCNRYITIRRKSEL 204

  Fly   387 AASLGLSNAQVITWFQNRRAKQKRDIEELKKDFDS 421
            |.:||||..||..||||||||:::.|::....|::
Mouse   205 AVNLGLSERQVKIWFQNRRAKERKMIKKKISQFEN 239

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
lbe	NP_524435.2	Homeodomain	354..410	CDD:459649	27/55 (49%)
Cdx4	NP_031700.1	Caudal_act	13..168	CDD:461413	56/352 (16%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	13..36		8/22 (36%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	98..156		22/179 (12%)
		Homeodomain	173..228	CDD:459649	27/54 (50%)