DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment lbl and lbx1

DIOPT Version :9

Sequence 1:	NP_001262805.1	Gene:	lbl / 42541	FlyBaseID:	FBgn0008651	Length:	410	Species:	Drosophila melanogaster
Sequence 2:	NP_001072559.1	Gene:	lbx1 / 780014	XenbaseID:	XB-GENE-6455157	Length:	265	Species:	Xenopus tropicalis

Alignment Length:	137	Identity:	80/137 - (58%)
Similarity:	95/137 - (69%)	Gaps:	19/137 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly   202 SPEEQPKGA-----SKS--SGDTPLDALFQLSTKNFD----------EEQDPATLNIFATRSNPK 249
            |..|:|..|     |::  |..:||.||.:|::|.|.          |.:|..|  ||..|..||
Frog    61 STAEKPPAAGLPLSSRALLSQTSPLCALEELASKTFKGLEVSVLQAAEGRDGMT--IFGQRQTPK 123

  Fly   250 KKRKSRTAFTNQQIFELEKRFLYQKYLSPADRDEIAGGLGLSNAQVITWFQNRRAKLKRDMEELK 314
            |:|||||||||.||:||||||||||||||||||:||..|||:||||||||||||||||||:||:|
Frog   124 KRRKSRTAFTNHQIYELEKRFLYQKYLSPADRDQIAQQLGLTNAQVITWFQNRRAKLKRDLEEMK 188

  Fly   315 KDVQCEK 321
            .||:..|
Frog   189 ADVESVK 195

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
lbl	NP_001262805.1	COG5576	206..332	CDD:227863	78/133 (59%)
lbl	NP_001262805.1	Homeobox	254..307	CDD:278475	46/52 (88%)
lbx1	NP_001072559.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..33
		Homeobox	128..182	CDD:365835	47/53 (89%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	212..265
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	107	1.000	Domainoid score	I6422
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1472248at2759
OrthoFinder	1	1.000	-	-		FOG0002643
OrthoInspector	1	1.000	-	-		mtm9428
Panther	1	1.100	-	-	O	PTHR24336
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R5376
SonicParanoid	1	1.000	-	-		X3367
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	9	9.050