Protein Alignment lbl and hmx2

DIOPT Version :10

• Sequence 1: NP_001262805.1
• Gene: lbl / 42541
• FlyBaseID: FBgn0008651
• Length: 410
• Species: Drosophila melanogaster
• Sequence 2: NP_001108570.3
• Gene: hmx2 / 555632
• ZFINID: ZDB-GENE-080506-2
• Length: 269
• Species: Danio rerio
• Alignment Length: 312
• Identity: 70/312 - (22%)
• Similarity: 108/312 - (34%)
• Gaps: 123/312 - (39%)

  Fly    41 EHDRQKSSPVRVKSFSIADILGRGHEEDRVEKKPERIAIPNALPGVPAPLALINERLQIPLVPNC 105
            |....|.||..:.||:|..|||..::..|...|..    |.:.|
Zfish     5 EDSGSKCSPAPISSFTIQSILGTSNDGVRSAGKDS----PKSQP--------------------- 44

  Fly   106 PPPAALHTFLSPALLHSYEQRLAWDYQRQLQEHFQAQAQLLRQMTLNPAIIASEDGSSERSQRSS 170
                                                     |:.||:   ::|||..|.......
Zfish    45 -----------------------------------------RKRTLS---VSSEDDCSAGEDSGD 65

  Fly   171 ---SSNGSTECCSPTQ---------------AEKVEKRSQEDRMEVPKKSP-------EEQPKGA 210
               |..|..|.|:|.|               .:.:::|        |..:|       |||.:..
Zfish    66 CYCSEPGVPESCNPHQPLNFCLGATKGLLPVQDGIDRR--------PHLTPSILPDYKEEQGRAC 122

  Fly   211 SKSSGDTPLDALFQLSTKNFDEEQDPATLNIFATRSNPKKKRKSRTAFTNQQIFELEKRFLYQKY 275
            |            |:|..:.|.::|.      ..:.|...|:|:||.|:..|:::||..|..::|
Zfish   123 S------------QMSPVSEDRQRDG------PDKQNNSAKKKTRTVFSRSQVYQLESTFDMKRY 169

  Fly   276 LSPADRDEIAGGLGLSNAQVITWFQNRRAKLKRDMEELKKDVQCEKIPDQSA 327
            ||.::|..:|..|.|:..||.|||||||.|.||   :|..:::...:...||
Zfish   170 LSSSERACLASSLQLTETQVKTWFQNRRNKWKR---QLSAELEAANMAHASA 218

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
lbl	NP_001262805.1	COG5576	206..332	CDD:227863	38/122 (31%)
		Homeodomain	252..308	CDD:459649	25/55 (45%)
hmx2	NP_001108570.3	Homeodomain	146..202	CDD:459649	25/55 (45%)