DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment lbl and hoxb3

DIOPT Version :9

Sequence 1:	NP_001262805.1	Gene:	lbl / 42541	FlyBaseID:	FBgn0008651	Length:	410	Species:	Drosophila melanogaster
Sequence 2:	NP_001015971.1	Gene:	hoxb3 / 548725	XenbaseID:	XB-GENE-482576	Length:	386	Species:	Xenopus tropicalis

Alignment Length:	301	Identity:	71/301 - (23%)
Similarity:	120/301 - (39%)	Gaps:	74/301 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly   116 SPALLHSYEQR---LAWDYQRQ-------LQEHFQAQAQLLRQMTLNPAIIASE--DGSSERSQR 168
            :|.|...|..:   |.::..:|       :...||..:..|:.:..:..::.::  :||..|...
Frog     9 NPTLFGGYPYQAGSLGYEGPQQSFPTSSHMDNEFQRSSCSLQSLGHSGPLVKAKNLNGSCMRPNL 73

  Fly   169 SSSSNGSTECCSPTQAEKVEKRSQEDRMEVPKKSPEEQPKGASKSSGDTPLDALF------QLST 227
            ||.   .::..|||........|...:..:.|.||.:     |::||......:|      :.::
Frog    74 SSE---QSQPLSPTANPSSNTNSSSSQASLSKPSPAK-----SQASGSPASKQIFPWMKESRQNS 130

  Fly   228 KNFDEEQDPATLNIFATRSNP--KKKRKSRTAFTNQQIFELEKRFLYQKYLSPADRDEIAGGLGL 290
            |.......||..:....||.|  ...:::|||:|:.|:.||||.|.:.:||....|.|:|..|.|
Frog   131 KQKSSPPAPAAESCGGDRSPPGSSASKRARTAYTSAQLVELEKEFHFNRYLCRPRRVEMANLLNL 195

  Fly   291 SNAQVITWFQNRRAKLKRDMEELKKDVQCEKIPDQS-----ADP--------------------- 329
            |..|:..||||||.|.|:|          :|:...|     |.|
Frog   196 SERQIKIWFQNRRMKYKKD----------QKVKGMSSSSGGASPTSTPPLSMQSSAGFLGSMHSM 250

  Fly   330 --NRSHHNHPHYHQQHQHYAHMQSIGSDRDMDKDRCREKEK 368
              |....:.|.:::.||: |:.|:.|..       |..::|
Frog   251 TANYEAPSPPPFNKSHQN-AYYQNPGKG-------CPSQQK 283

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
lbl	NP_001262805.1	COG5576	206..332	CDD:227863	43/161 (27%)
lbl	NP_001262805.1	Homeobox	254..307	CDD:278475	26/52 (50%)
hoxb3	NP_001015971.1	Homeobox	160..212	CDD:306543	26/51 (51%)
hoxb3	NP_001015971.1	DUF4074	325..384	CDD:315871
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910