Protein Alignment lbl and HGTX

DIOPT Version :10

• Sequence 1: NP_001262805.1
• Gene: lbl / 42541
• FlyBaseID: FBgn0008651
• Length: 410
• Species: Drosophila melanogaster
• Sequence 2: NP_001368954.1
• Gene: HGTX / 53446
• FlyBaseID: FBgn0040318
• Length: 587
• Species: Drosophila melanogaster
• Alignment Length: 474
• Identity: 105/474 - (22%)
• Similarity: 150/474 - (31%)
• Gaps: 190/474 - (40%)

  Fly     2 PQRTPSPANSDV-SVGSPSPPPLRSLNMKRLRLLRSPISLEHDRQKSSP--VRVKSFSIADILGR 63
            |..||.||:|.: |..||||                  ..||:   |||  ...||::::. ...
  Fly   179 PSTTPPPASSRLHSDSSPSP------------------RYEHN---SSPGVDSAKSYALSQ-RSS 221

  Fly    64 GHE-------------EDRVEKKPERIAIPNAL----PGVPAPLALINER--------------- 96
            |.|             :.:.:..||.::...|.    .|| .||||.|..
  Fly   222 GAEDPCQTSESASPPPQGQNDYSPENLSSQRAKFQHHHGV-NPLALHNANHAGNPGCHNNNNHMD 285

  Fly    97 LQIPLVPNCPPPAALHTFLSPALLHSYEQRLAWDYQRQLQEHFQAQAQLLRQMTLNPAIIASEDG 161
            .::||....||.||||:             :..:.:.|......|.|..|.......:.:.|:.|
  Fly   286 HKLPLSFLGPPLAALHS-------------MTTEMKGQGVGGSSASANGLSYSHSPNSHLISDRG 337

  Fly   162 SSERSQRSSSSNGSTECCSPTQAEKVEKRSQEDRMEVPKKSPEEQPKGASKSSG----------- 215
            |...|..||::..:|..........::        .:..|.|.....|.|..:|
  Fly   338 SGGSSSSSSTTTTNTNSQGAPNPHGID--------TILSKPPPVTSAGLSALTGAGIPRFSIAAA 394

  Fly   216 ------------DTPL-----------------------------DALFQLSTKNFDE--EQDPA 237
                        ..||                             :.|....:.|..:  :..|
  Fly   395 AAGMAQYLSQSQGAPLKTHAGHIVDRTHLYWPGLQGLVANPIAWRERLSNTMSANLSQSHQHHP- 458

  Fly   238 TLNIFATRSNPK--KKRKSRTAFTNQQIFELEKRFLYQKYLSPADRDEIAGGLGLSNAQVITWFQ 300
                    ||.|  ||:.:|..|:.||||.|||.|...|||:..:|.::|..||:|.:||..|||
  Fly   459 --------SNDKDGKKKHTRPTFSGQQIFALEKTFEQTKYLAGPERAKLAYALGMSESQVKVWFQ 515

  Fly   301 NRRAKLKRDMEELKKDVQCEKIPDQSADPNRSHHNHPHYHQQHQHYAHM-------QSIGSDRDM 358
            |||.|.::                                   :|.|.|       ..:|.|.|.
  Fly   516 NRRTKWRK-----------------------------------RHAAEMATAKRKQDDMGGDNDG 545

  Fly   359 DKDRCREKEKDKDKEELRM 377
            |   |.| ..|.|.|.|.|
  Fly   546 D---CSE-TMDSDNESLDM 560

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
lbl	NP_001262805.1	COG5576	206..332	CDD:227863	40/181 (22%)
		Homeodomain	252..308	CDD:459649	27/55 (49%)
HGTX	NP_001368954.1	ROM1	179..>388	CDD:227709	54/252 (21%)
		Homeodomain	465..523	CDD:459649	29/57 (51%)