Protein Alignment lbl and NKX3-1

DIOPT Version :10

• Sequence 1: NP_001262805.1
• Gene: lbl / 42541
• FlyBaseID: FBgn0008651
• Length: 410
• Species: Drosophila melanogaster
• Sequence 2: NP_006158.2
• Gene: NKX3-1 / 4824
• HGNCID: 7838
• Length: 234
• Species: Homo sapiens
• Alignment Length: 201
• Identity: 54/201 - (26%)
• Similarity: 92/201 - (45%)
• Gaps: 41/201 - (20%)

  Fly   184 AEKVEKRSQEDRMEVPKKSPEEQPKGASKSSG---DTPLDALFQLST---------KNFDEEQDP 236
            |::...|:...|...|:..||.:|:|....:|   |       ||||         :...|.:..
Human    39 AQRQGGRTSSQRQRDPEPEPEPEPEGGRSRAGAQND-------QLSTGPRAAPEEAETLAETEPE 96

  Fly   237 ATLNIFATRS------------NPKK-KRKSRTAFTNQQIFELEKRFLYQKYLSPADRDEIAGGL 288
            ..|..:...|            .||: :::||.||::.|:.|||::|.:|||||..:|..:|..|
Human    97 RHLGSYLLDSENTSGALPRLPQTPKQPQKRSRAAFSHTQVIELERKFSHQKYLSAPERAHLAKNL 161

  Fly   289 GLSNAQVITWFQNRRAKLKR-----DMEELKKDVQCEKIPDQSADPNRSHHNHPHYHQQHQHYAH 348
            .|:..||..||||||.|.||     ::.:|:|......:.:::.    |..:....:..:.:|.:
Human   162 KLTETQVKIWFQNRRYKTKRKQLSSELGDLEKHSSLPALKEEAF----SRASLVSVYNSYPYYPY 222

  Fly   349 MQSIGS 354
            :..:||
Human   223 LYCVGS 228

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
lbl	NP_001262805.1	COG5576	206..332	CDD:227863	44/155 (28%)
		Homeodomain	252..308	CDD:459649	27/55 (49%)
NKX3-1	NP_006158.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..131		21/98 (21%)
		Homeodomain	125..181	CDD:459649	27/55 (49%)