Protein Alignment lbl and E5

DIOPT Version :10

• Sequence 1: NP_001262805.1
• Gene: lbl / 42541
• FlyBaseID: FBgn0008651
• Length: 410
• Species: Drosophila melanogaster
• Sequence 2: NP_524825.1
• Gene: E5 / 45396
• FlyBaseID: FBgn0008646
• Length: 524
• Species: Drosophila melanogaster
• Alignment Length: 505
• Identity: 97/505 - (19%)
• Similarity: 147/505 - (29%)
• Gaps: 237/505 - (46%)

  Fly     4 RTPSPANS--------------DVSVGSPSPP------PLRSLNMKRLRLLRSPISL-------E 41
            |:|||.|:              |.|.|:.:||      ||.:.|:..:....||.::       .
  Fly   122 RSPSPPNAGGNPAAAGNTAKSGDPSSGTGNPPTLIRPLPLPAPNLALIGNRTSPNAMAVRMAGPP 186

  Fly    42 HDRQKSSPVRVKSFSIADILGRGHEEDRVEKKPERIAIPNALPGVPAPLALINERL---QIPL-- 101
            |...:..|.....|.:|..|...|::.:.:::.:...:|...|..|.|      .|   ||||
  Fly   187 HPPSQPPPFLAAQFQMAAALAHHHQQQQQQQQQQLPPVPTGPPHGPHP------HLPPGQIPLGI 245

  Fly   102 -----VPNCPPPAALHTFLS-PALLHSYEQRLAWDYQRQLQEHFQAQAQLLRQMTLNPAIIASED 160
                 .|..|||...|.|.| |.|:........|              .|.|...:.|..
  Fly   246 FPGGPHPGHPPPHGHHPFGSAPHLIRDSYPLYPW--------------LLSRHGRIFPRF----- 291

  Fly   161 GSSERSQRSSSSNGSTECCSPTQAEKVEKRSQEDRMEVPKKSPEEQPKGASKSSGDTPLDALFQL 225
                                                                     |.:.|||
  Fly   292 ---------------------------------------------------------PGNFLFQ- 298

  Fly   226 STKNFDEEQDPATLNIFATRSNP-KKKRKSRTAFTNQQIFELEKRFLYQKYLSPADRDEIAGGLG 289
                                  | :|.::.||||:..|:.:||..|....|:..|:|.::|.||.
  Fly   299 ----------------------PFRKPKRVRTAFSPTQLLKLEHAFEGNHYVVGAERKQLAQGLS 341

  Fly   290 LSNAQVITWFQNRRAKLKR---------------------------------------------- 308
            |:..||..||||||.|.||
  Fly   342 LTETQVKVWFQNRRTKHKRMQQEGGDGSDTKSNKGSSSGGGGGGDGEDDAKHDGSQHSYEDAEDP 406

  Fly   309 -DMEELKKDVQCEKI--------------------------------------------PDQSAD 328
             |.:|:::|.:.|.|                                            |.|...
  Fly   407 EDEDEIEEDDEDEVIDMDDYGSEMDAEEHQRLREQFQQQLAQHQQQFMQQNAGEAATLSPQQQHQ 471

  Fly   329 PNRSHHNH--PHYHQQHQHYAHMQSIGSDRDMDKDRCREKEKDKDKEELR 376
            ..:.|..|  ..:|||.||:...|.....|:.:::|.||:|::::|...|
  Fly   472 LLQQHQQHLQQQHHQQQQHFIQQQQQLYLREREREREREREREREKSRER 521

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
lbl	NP_001262805.1	COG5576	206..332	CDD:227863	39/217 (18%)
		Homeodomain	252..308	CDD:459649	24/55 (44%)
E5	NP_524825.1	Homeodomain	304..360	CDD:459649	24/55 (44%)