Protein Alignment lbl and MSX2

DIOPT Version :10

• Sequence 1: NP_001262805.1
• Gene: lbl / 42541
• FlyBaseID: FBgn0008651
• Length: 410
• Species: Drosophila melanogaster
• Sequence 2: NP_002440.2
• Gene: MSX2 / 4488
• HGNCID: 7392
• Length: 267
• Species: Homo sapiens
• Alignment Length: 198
• Identity: 58/198 - (29%)
• Similarity: 89/198 - (44%)
• Gaps: 42/198 - (21%)

  Fly   153 PAIIA--------SEDGSSERSQRSSSSNGSTECCSPTQAEKVEKRSQEDRMEVPKKSPEE---- 205
            ||::|        :|..:.||..:.||...|.|      |...:|:..::...:|.:|...
Human    18 PAVVAGPGPGPGGAEGAAEERRVKVSSLPFSVE------ALMSDKKPPKEASPLPAESASAGATL 76

  Fly   206 QP-----KGASKSSGDTPLDALFQLSTKNFDEEQDPATLNIFATRSNP---------------KK 250
            :|     .||.::....||...|:.::...:..:|.|.......|.:|               |.
Human    77 RPLLLSGHGAREAHSPGPLVKPFETASVKSENSEDGAAWMQEPGRYSPPPRHMSPTTCTLRKHKT 141

  Fly   251 KRKSRTAFTNQQIFELEKRFLYQKYLSPADRDEIAGGLGLSNAQVITWFQNRRAKLKR----DME 311
            .||.||.||..|:..||::|..::|||.|:|.|.:..|.|:..||..||||||||.||    ::|
Human   142 NRKPRTPFTTSQLLALERKFRQKQYLSIAERAEFSSSLNLTETQVKIWFQNRRAKAKRLQEAELE 206

  Fly   312 ELK 314
            :||
Human   207 KLK 209

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
lbl	NP_001262805.1	COG5576	206..332	CDD:227863	44/133 (33%)
		Homeodomain	252..308	CDD:459649	28/55 (51%)
MSX2	NP_002440.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..71		14/58 (24%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	116..147		5/30 (17%)
		Homeodomain	143..199	CDD:459649	28/55 (51%)