Protein Alignment lbl and nkx6.1

DIOPT Version :10

• Sequence 1: NP_001262805.1
• Gene: lbl / 42541
• FlyBaseID: FBgn0008651
• Length: 410
• Species: Drosophila melanogaster
• Sequence 2: NP_001002475.1
• Gene: nkx6.1 / 436748
• ZFINID: ZDB-GENE-040718-178
• Length: 312
• Species: Danio rerio
• Alignment Length: 355
• Identity: 82/355 - (23%)
• Similarity: 122/355 - (34%)
• Gaps: 113/355 - (31%)

  Fly   104 NCPPPAALH--TFLSPALLHSYEQRLAWDYQRQLQEHFQAQAQLLRQMTLNPAIIASEDGSSERS 166
            |.||.||||  |.:...|..:|          .|.....|.:......:.||..|.......:.|
Zfish    18 NTPPLAALHSMTEMKTPLYPAY----------PLSSTGPASSTSPTATSPNPGGIPVSSPGIKTS 72

  Fly   167 QRSSSSNGSTEC------------------CSPTQAEKVEKRSQEDRMEVPKK-----SPE---- 204
            ...|:...:.:|                  |||  |..:....:...:..|..     ||.
Zfish    73 SGLSALASAQQCAIATPHGINDILSRPSVACSP--AGILSGLPRFSSLSPPPPPGLYFSPSAAAV 135

  Fly   205 ---EQPKGASKSSGDTPL------------DALFQLSTKNFDEEQDPATLNIFATRSNPKKKRKS 254
               ..||..::..|.||:            ||.|..|     ..|:...|:      ...|::.:
Zfish   136 AVARYPKPLTELPGRTPIFWPGVMQSPHWRDARFACS-----PHQNSVLLD------KDGKRKHT 189

  Fly   255 RTAFTNQQIFELEKRFLYQKYLSPADRDEIAGGLGLSNAQVITWFQNRRAK-LKRDMEEL----- 313
            |..|:.||||.|||.|...|||:..:|..:|..||::.:||..||||||.| .||...|:
Zfish   190 RPTFSGQQIFALEKTFEQTKYLAGPERARLAYSLGMTESQVKVWFQNRRTKWRKRHAAEMASAKK 254

  Fly   314 KKDVQCEKIPDQSADPNRSHHNHPHYHQQHQHYAHMQSIGSDRDMDKDRCREKEKDKDKEELRML 378
            |:|.:.|::...|                           .:.|.|.|..:..:.:.|.|::.
Zfish   255 KQDSETERLKGAS---------------------------ENEDDDDDYNKPLDPNSDDEKIT-- 290

  Fly   379 KLMTLMRYSDGKLLYQQPPASYLPIPHRQN 408
                       :||.:..|.|.|.|...:|
Zfish   291 -----------QLLKKHKPNSALIIHTSEN 309

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
lbl	NP_001262805.1	COG5576	206..332	CDD:227863	45/143 (31%)
		Homeodomain	252..308	CDD:459649	26/56 (46%)
nkx6.1	NP_001002475.1	Homeodomain	185..243	CDD:459649	27/57 (47%)