Protein Alignment lbl and MEOX1

DIOPT Version :10

• Sequence 1: NP_001262805.1
• Gene: lbl / 42541
• FlyBaseID: FBgn0008651
• Length: 410
• Species: Drosophila melanogaster
• Sequence 2: NP_004518.1
• Gene: MEOX1 / 4222
• HGNCID: 7013
• Length: 254
• Species: Homo sapiens
• Alignment Length: 279
• Identity: 71/279 - (25%)
• Similarity: 99/279 - (35%)
• Gaps: 111/279 - (39%)

  Fly   102 VPNCPP-PAALH---TFLSPALL--------------HSYEQRLAWDYQRQLQEH-FQAQAQLLR 147
            :|:.|| |.:.|   .||:.|..              ||..|          :|| |..|
Human    35 LPHYPPTPFSFHQKPDFLATATAAYPDFSASCLAATPHSLPQ----------EEHIFTEQ----- 84

  Fly   148 QMTLNPAIIASED-----GSSERSQRSSSSNGSTECCSP-------------------TQAEKVE 188
                :||...|.:     ..:.|...|..:.||.|..:.                   :.|.:.|
Human    85 ----HPAFPQSPNWHFPVSDARRRPNSGPAGGSKEMGTSSLGLVDTTGGPGDDYGVLGSTANETE 145

  Fly   189 KRSQEDRMEVPKKSPEEQ-----PKGASKSSGDTPLDALFQLSTKNFDEEQDPATLNIFATRSNP 248
            |:|...|    |:|.:.|     |:|:||:
Human   146 KKSSRRR----KESSDNQENRGKPEGSSKA----------------------------------- 171

  Fly   249 KKKRKSRTAFTNQQIFELEKRFLYQKYLSPADRDEIAGGLGLSNAQVITWFQNRRAKLKR--DME 311
               ||.|||||.:|:.|||..|.:..||:...|.|||..|.||..||..||||||.|.||  ..:
Human   172 ---RKERTAFTKEQLRELEAEFAHHNYLTRLRRYEIAVNLDLSERQVKVWFQNRRMKWKRVKGGQ 233

  Fly   312 ELKKDVQCEKIPDQSADPN 330
            .:..:.|..:..|.:|.|:
Human   234 PISPNGQDPEDGDSTASPS 252

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
lbl	NP_001262805.1	COG5576	206..332	CDD:227863	41/132 (31%)
		Homeodomain	252..308	CDD:459649	30/55 (55%)
MEOX1	NP_004518.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	86..178		24/133 (18%)
		Homeodomain	172..228	CDD:459649	30/55 (55%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	227..254		6/26 (23%)