Protein Alignment lbl and Hmx

DIOPT Version :10

• Sequence 1: NP_001262805.1
• Gene: lbl / 42541
• FlyBaseID: FBgn0008651
• Length: 410
• Species: Drosophila melanogaster
• Sequence 2: NP_001262674.1
• Gene: Hmx / 42110
• FlyBaseID: FBgn0264005
• Length: 718
• Species: Drosophila melanogaster
• Alignment Length: 480
• Identity: 108/480 - (22%)
• Similarity: 173/480 - (36%)
• Gaps: 163/480 - (33%)

  Fly    54 SFSIADILGRGHEEDRVEKKPERIAIPNALPGVPAPLALINERLQIPLVPNCPPPAALHT---FL 115
            ||||:.||.|...    .||.....:...:|.:|.|.|            ..|..||:.:   |:
  Fly   233 SFSISSILSRSEP----AKKNGAAGLITPIPQLPQPGA------------GGPQDAAMLSRLGFI 281

  Fly   116 SP--ALLHSYEQRL--AWDYQRQ-LQEHFQAQAQLLRQMTLNP--AIIASEDGSSERSQRSSSSN 173
            |.  ||...|....  .|.:..| |..|...........|.||  ....|.:.::..|..::|||
  Fly   282 SQWGALAGRYAALCPPGWPWAPQRLPFHSPTHDSSSTNTTENPPSPTSMSPNNNNNNSNTTASSN 346

  Fly   174 GSTECCSPTQ----------AEKVEKRSQEDRMEVPKKS--PEEQ----------PKGASKSSGD 216
            .:::  ||:.          ..:.:::.|:...:.|::.  |::|          |..:|.|.|.
  Fly   347 QASK--SPSHHPLHPLYHPLGSQQQQQQQQQHQQHPQQQQHPQQQQQQHPHQPTTPTSSSSSGGG 409

  Fly   217 TPL-------------DALFQLSTKNFDE------EQDPATLNIFATRS-----NPKKKRKSRTA 257
            :.|             ..|...|:...||      |:|..|.....:.|     |.|:|:|:||.
  Fly   410 SSLTHHPHPHLTGSHGGYLLPSSSNESDEEGEEIIEEDDGTDGPSDSSSPHGDGNSKRKKKTRTV 474

  Fly   258 FTNQQIFELEKRFLYQKYLSPADRDEIAGGLGLSNAQVITWFQNRRAKLKRDMEELKKDVQCEKI 322
            |:..|:|:||..|..::|||.::|..:|..|.|:..||..||||||.|.||   :|..:::...:
  Fly   475 FSRAQVFQLESTFDLKRYLSSSERAGLAASLRLTETQVKIWFQNRRNKWKR---QLAAELEAANM 536

  Fly   323 PDQSADPNR------SHHN----------HPHYHQQHQHYA------------------------ 347
            .:.:....|      .:|:          .||:|.. |:||
  Fly   537 ANMAHAAQRLVRVPVLYHDGTTAGFVPPPPPHHHPM-QYYAAARNTSPPRPPLSSLVXGVGCLAT 600

  Fly   348 --------------------------HMQS---IG----SDRDMDKDRCREKEKDKDKEELRMLK 379
                                      |||.   :|    ::.|||.|..:|:....|.|:..:
  Fly   601 APMSLLKPPNSMAHPPHPQPPPPAPLHMQQRSFLGCEQLTETDMDSDSEQERSHMMDDEDAAI-- 663

  Fly   380 LMTLMRYSDGKLLYQQPPASYLPIP 404
                    |.:...:|..||  |:|
  Fly   664 --------DVEADEEQESAS--PVP 678

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
lbl	NP_001262805.1	COG5576	206..332	CDD:227863	46/165 (28%)
		Homeodomain	252..308	CDD:459649	25/55 (45%)
Hmx	NP_001262674.1	Homeodomain	469..525	CDD:459649	25/55 (45%)