Protein Alignment lbl and cdx1

DIOPT Version :10

• Sequence 1: NP_001262805.1
• Gene: lbl / 42541
• FlyBaseID: FBgn0008651
• Length: 410
• Species: Drosophila melanogaster
• Sequence 2: NP_989416.1
• Gene: cdx1 / 395055
• XenbaseID: XB-GENE-485396
• Length: 262
• Species: Xenopus tropicalis
• Alignment Length: 170
• Identity: 48/170 - (28%)
• Similarity: 72/170 - (42%)
• Gaps: 33/170 - (19%)

  Fly   169 SSSSNGSTECCSPTQAEKVEKRSQEDRMEVPKKSPEEQPKG-----ASKSSGDTPLDALFQLSTK 228
            :||:|.:....||:....|                  ||.|     .|.:|..:||....|  .:
 Frog    81 ASSANPAQISFSPSDYNPV------------------QPPGPGLLPPSLNSSVSPLSPSAQ--RR 125

  Fly   229 NFDEEQD----PATLNIFATRSNPKKKRKSRTAFTNQQIFELEKRFLYQKYLSPADRDEIAGGLG 289
            |..|...    |.:.|   :....:.|.|.|..:|:.|..||||.|.|.:|::...:.|:|..|.
 Frog   126 NLYEWMRRTGVPTSTN---SNGKTRTKDKYRVVYTDHQRLELEKEFHYSRYITIRRKAELAASLA 187

  Fly   290 LSNAQVITWFQNRRAKLKRDMEELKKDVQCEKIPDQSADP 329
            |:..||..|||||||| :|.:.:.|...|.::....:..|
 Frog   188 LTERQVKIWFQNRRAK-ERKVNKKKMQQQSQQASTTTPTP 226

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
lbl	NP_001262805.1	COG5576	206..332	CDD:227863	42/133 (32%)
		Homeodomain	252..308	CDD:459649	25/55 (45%)
cdx1	NP_989416.1	Caudal_act	13..141	CDD:461413	17/79 (22%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	42..120		13/56 (23%)
		Homeodomain	151..206	CDD:459649	25/55 (45%)
		Interaction with DNA. /evidence=ECO:0000250|UniProtKB:P47902	152..173		9/20 (45%)
		Interaction with 5-mCpG DNA. /evidence=ECO:0000250|UniProtKB:P47902	191..202		7/10 (70%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	203..262		5/25 (20%)