Protein Alignment lbl and en

DIOPT Version :10

• Sequence 1: NP_001262805.1
• Gene: lbl / 42541
• FlyBaseID: FBgn0008651
• Length: 410
• Species: Drosophila melanogaster
• Sequence 2: NP_523700.2
• Gene: en / 36240
• FlyBaseID: FBgn0000577
• Length: 552
• Species: Drosophila melanogaster
• Alignment Length: 389
• Identity: 91/389 - (23%)
• Similarity: 141/389 - (36%)
• Gaps: 120/389 - (30%)

  Fly    12 DVSVGSPSPPPLRSLNMKRLRLLRSPISLEHDRQKSSPVRVKSFSIADIL----------GRGHE 66
            |.|.|...|||                  .|.:|.::...: :|||::||          |:..|
  Fly   151 DTSAGGRLPPP------------------AHQQQSTAKPSL-AFSISNILSDRFGDVQKPGKSME 196

  Fly    67 EDR-----VEKKPERIAIPNALPGV--------------PAPLALINERLQIPLVPNCPPPAA-- 110
            ...     .|....:.|.|:|...|              .|..|::.||...   .||..|||
  Fly   197 NQASIFRPFEASRSQTATPSAFTRVDLLEFSRQQQAAAAAATAAMMLERANF---LNCFNPAAYP 258

  Fly   111 -LHTFLSPALLH-------------------SYEQRLAWDYQRQLQEHFQAQAQLLRQMTLN--- 152
             :|..:..:.|.                   :.|:.......:.:.:..|..|..:.|..|:
  Fly   259 RIHEEIVQSRLRRSAANAVIPPPMSSKMSDANPEKSALGSLCKAVSQIGQPAAPTMTQPPLSSSA 323

  Fly   153 -------PAIIASEDGSSERSQRSSSSNGSTECCSPTQAEKVEKRSQEDRM---------EVPKK 201
                   ||..||.. ||..|..:|||:.|:.|.|   |......|...|:         ..|:.
  Fly   324 SSLASPPPASNASTI-SSTSSVATSSSSSSSGCSS---AASSLNSSPSSRLGASGSGVNASSPQP 384

  Fly   202 SPEEQPKGASKSSG----DTPLDALFQLSTKNFDEEQDPATLNIFATR--------------SNP 248
            .|...|...|:.||    |.........:|:....|..||.  ::.||              ..|
  Fly   385 QPIPPPSAVSRDSGMESSDDTRSETGSTTTEGGKNEMWPAW--VYCTRYSDRPSSGPRYRRPKQP 447

  Fly   249 KKK----RKSRTAFTNQQIFELEKRFLYQKYLSPADRDEIAGGLGLSNAQVITWFQNRRAKLKR 308
            |.|    ::.||||:::|:..|::.|...:||:...|.:::..|||:.||:..||||:|||:|:
  Fly   448 KDKTNDEKRPRTAFSSEQLARLKREFNENRYLTERRRQQLSSELGLNEAQIKIWFQNKRAKIKK 511

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
lbl	NP_001262805.1	COG5576	206..332	CDD:227863	37/125 (30%)
		Homeodomain	252..308	CDD:459649	22/55 (40%)
en	NP_523700.2	Homeodomain	455..511	CDD:459649	22/55 (40%)
		Engrail_1_C_sig	512..542	CDD:431338	91/389 (23%)