Protein Alignment lbl and HOXC10

DIOPT Version :10

• Sequence 1: NP_001262805.1
• Gene: lbl / 42541
• FlyBaseID: FBgn0008651
• Length: 410
• Species: Drosophila melanogaster
• Sequence 2: NP_059105.2
• Gene: HOXC10 / 3226
• HGNCID: 5122
• Length: 342
• Species: Homo sapiens
• Alignment Length: 331
• Identity: 84/331 - (25%)
• Similarity: 125/331 - (37%)
• Gaps: 84/331 - (25%)

  Fly     6 PSPANSDVSVGSPS------PPPLRSLNM----KRLRLLRSPISLEHDRQKSS---PVRVKSFSI 57
            ||.:..|.. .|||      |..|..|:.    |....|..|:.    |..||   |..||..::
Human    51 PSLSKRDEG-SSPSLALNTYPSYLSQLDSWGDPKAAYRLEQPVG----RPLSSCSYPPSVKEENV 110

  Fly    58 ADILGRGHEEDRVEKKPERIAIPNALPGVPAPLALINERLQIPL---------------VPNCPP 107
            ..:..   .|.|.:..||.     ||...|.|.:.:.|. ::|:               .|:|
Human   111 CCMYS---AEKRAKSGPEA-----ALYSHPLPESCLGEH-EVPVPSYYRASPSYSALDKTPHC-- 164

  Fly   108 PAALHTFLSPALLHSYEQRLAWDYQRQLQEHFQAQAQLLRQMTLNPAIIASEDGSSERSQRSSSS 172
             :..:.|.:|     :|||.:          ...:|:.|....|...:...|...|: ||..|.:
Human   165 -SGANDFEAP-----FEQRAS----------LNPRAEHLESPQLGGKVSFPETPKSD-SQTPSPN 212

  Fly   173 NGSTECCSPTQAEKVEKRSQEDRMEVPKKSPEEQPKGASKSSGDTPLDALFQLSTKNFDEEQDPA 237
            ...|                |..:..||.||.|..|..:|::..:|       .|.:.:.:::..
Human   213 EIKT----------------EQSLAGPKGSPSESEKERAKAADSSP-------DTSDNEAKEEIK 254

  Fly   238 TLNIFATRSNPKKKRKSRTAFTNQQIFELEKRFLYQKYLSPADRDEIAGGLGLSNAQVITWFQNR 302
            ..|........|..||.|..:|..|..||||.||:..||:...|.||:..:.|::.||..|||||
Human   255 AENTTGNWLTAKSGRKKRCPYTKHQTLELEKEFLFNMYLTRERRLEISKTINLTDRQVKIWFQNR 319

  Fly   303 RAKLKR 308
            |.|||:
Human   320 RMKLKK 325

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
lbl	NP_001262805.1	COG5576	206..332	CDD:227863	34/103 (33%)
		Homeodomain	252..308	CDD:459649	27/55 (49%)
HOXC10	NP_059105.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..29
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	187..271		21/107 (20%)
		Homeodomain	269..325	CDD:459649	27/55 (49%)